KRT15 and MAD2L1BP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT15	MAD2L1BP
Gene Name		keratin 15, type I	MAD2L1 binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Intermediate Filament Extracellular Vesicular Exosome	Nucleus Nucleolus Cytoplasm Spindle Intracellular Membrane-bounded Organelle
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Epidermis Development	Mitotic Cell Cycle Checkpoint Regulation Of Exit From Mitosis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		115 interactors: ABI2 ABI3 ABLIM1 AES ALS2CR11 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5O BEX2 C10orf10 C1orf216 CALCOCO1 CCDC101 CCDC120 CCDC185 CCDC67 CCDC87 CCHCR1 CCNB1IP1 CCNC CEP57 COX5B CREB5 CYTH4 DGCR6L EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT18 KRT19 KRT20 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT73 KRT77 KRT79 KRT8 KRT80 KRT81 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RCOR3 RHPN1 RIBC1 RIBC2 SIRPA SMARCD1 SMARCE1 SPG21 SSX2IP TCHP TEKT4 TIMM8A TMSB4X TRIM42 TSG101 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638	15 interactors: EEF1A1 HOMEZ IGSF21 INPP5K KAT5 KIAA1377 KRT15 LRIF1 MAD2L1 NMI PTN SETDB1 TP53 TRIP13 ZBTB14
Entrez ID		3866	9587
HPRD ID		01009	10065
Ensembl ID		ENSG00000171346	ENSG00000124688
Uniprot IDs		A8MT21 B3KVF5 P19012	Q15013
PDB IDs			2QYF
Enriched GO Terms of Interacting Partners?		Organelle Organization Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Cycle Cell Cycle Process Intermediate Filament Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Component Assembly Microtubule-based Process Mitotic Cell Cycle Chromosome Organization Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification Cellular Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Intraciliary Transport Involved In Cilium Morphogenesis Anatomical Structure Development RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Cell Cycle Checkpoint Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Gene Expression Movement Of Cell Or Subcellular Component Chromatin Remodeling Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Wnt Signaling Pathway RNA Metabolic Process Developmental Process Histone Acetylation Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Internal Protein Amino Acid Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Double-strand Break Repair Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Chromosome Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Renal Water Transport Negative Regulation Of Catalytic Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Organelle Organization Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Signal Transduction In Response To DNA Damage Negative Regulation Of DNA Metabolic Process Negative Regulation Of Helicase Activity Negative Regulation Of Glycogen (starch) Synthase Activity Signal Transduction By P53 Class Mediator Negative Regulation Of APC-Cdc20 Complex Activity Cell Cycle Process Regulation Of Gene Expression In Utero Embryonic Development Regulation Of Transcription From RNA Polymerase II Promoter Response To Ionizing Radiation Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Tagcloud ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape maged1 mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Difference) ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 vegfr	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape maged1 mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1
Tagcloud (Intersection) ?		transcriptome