KRT15 and ARFIP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT15	ARFIP2
Gene Name		keratin 15, type I	ADP-ribosylation factor interacting protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Intermediate Filament Extracellular Vesicular Exosome	Ruffle Cytoplasm Plasma Membrane Cell Cortex Trans-Golgi Network Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Protein Binding GTP Binding Protein Domain Specific Binding GTP-dependent Protein Binding Rac GTPase Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	Epidermis Development	Movement Of Cell Or Subcellular Component Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		115 interactors: ABI2 ABI3 ABLIM1 AES ALS2CR11 AMOT AMOTL2 ANKRD36BP1 APC ARC ARFIP2 ATP5O BEX2 C10orf10 C1orf216 CALCOCO1 CCDC101 CCDC120 CCDC185 CCDC67 CCDC87 CCHCR1 CCNB1IP1 CCNC CEP57 COX5B CREB5 CYTH4 DGCR6L EPC1 EXOC8 FAM107A FAM110A GFAP GLYCTK HAUS1 HGS HMG20B HOXB6 IKBIP KANSL1 KIAA0408 KIAA1217 KIFC3 KLC3 KLC4 KRT18 KRT19 KRT20 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT73 KRT77 KRT79 KRT8 KRT80 KRT81 KRT86 LDOC1 LMO2 LMO4 LNX1 MAD2L1BP MBD3 MCM10 MORN3 MOS NEFL NIF3L1 NOC4L NUDT18 NUP54 OIP5 PCM1 PIK3R2 PKN1 PPP1R18 PRPF31 PRPH PSMA1 PSMB1 PSMC5 RAD51D RCOR3 RHPN1 RIBC1 RIBC2 SIRPA SMARCD1 SMARCE1 SPG21 SSX2IP TCHP TEKT4 TIMM8A TMSB4X TRIM42 TSG101 TUBGCP4 TXLNA TXLNB TXNDC11 USHBP1 USP2 WAC ZC2HC1C ZFYVE26 ZGPAT ZNF417 ZNF576 ZNF638	26 interactors: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 CDKN2A CEP63 DTNBP1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 LY6D MAL2 RAC1 RAC2 SNX1 SOCS2 STAT3 TRIM54 USHBP1
Entrez ID		3866	23647
HPRD ID		01009	07209
Ensembl ID		ENSG00000171346	ENSG00000132254
Uniprot IDs		A8MT21 B3KVF5 P19012	B4DUZ3 B4DXH2 P53365
PDB IDs			1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?		Organelle Organization Cytoskeleton Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cell Cycle Cell Cycle Process Intermediate Filament Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Cellular Component Assembly Microtubule-based Process Mitotic Cell Cycle Chromosome Organization Microtubule Cytoskeleton Organization Chromatin Organization Chromatin Modification Cellular Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Intraciliary Transport Involved In Cilium Morphogenesis Anatomical Structure Development RNA Biosynthetic Process Negative Regulation Of Canonical Wnt Signaling Pathway Cell Cycle Checkpoint Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Gene Expression Movement Of Cell Or Subcellular Component Chromatin Remodeling Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Wnt Signaling Pathway RNA Metabolic Process Developmental Process Histone Acetylation Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Canonical Wnt Signaling Pathway Internal Protein Amino Acid Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process	Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Signaling Cell Communication Signal Transduction Vesicle-mediated Transport Cell Projection Organization Response To Stimulus Regulation Of Signaling Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Organelle Organization Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Protein Localization Cellular Localization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Growth Positive Regulation Of Cell Death Apoptotic Process Platelet Activation Protein Transport Programmed Cell Death Regulation Of Hydrogen Peroxide Metabolic Process Blood Coagulation Cell Death Death Cell Division Establishment Of Protein Localization Hemostasis Regulation Of Respiratory Burst Intracellular Transport Establishment Of Localization In Cell Regulation Of Cell Death Positive Regulation Of Lamellipodium Assembly Generation Of Neurons Golgi Vesicle Transport Protein Localization To Organelle Positive Regulation Of Lamellipodium Organization Neurogenesis Cell Projection Morphogenesis Membrane Invagination Cellular Copper Ion Homeostasis Negative Regulation Of JAK-STAT Cascade Cell Part Morphogenesis Positive Regulation Of Signal Transduction Developmental Process
Tagcloud ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr
Tagcloud (Difference) ?		17beta 3a additive canonical chemotherapeutic chosen combinatorial communications cooperation cooperative doxorubicin epha2 ers flt1 fuorouracil gdnf inpp5d mcf7 microarrays noncanonical notch1 nutlin responsiveness searches silenced sox9 tlr5 transcriptome vegfr
Tagcloud (Intersection) ?