KRT2 and KRT40

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT2	KRT40
Gene Name		keratin 2, type II	keratin 40, type I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Golgi Apparatus Intermediate Filament Membrane Keratin Filament Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome	Intermediate Filament
	Molecular Function	Structural Constituent Of Cytoskeleton	Structural Molecule Activity
	Biological Process	Epidermis Development Keratinization Keratinocyte Activation Keratinocyte Proliferation Keratinocyte Migration
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: EVPL KRT13 KRT19 KRT31 KRT38 KRT40 SMAD3	313 interactors: ADAMTSL3 AEN AES AKAP17A ALDH3B1 ALS2CR11 ANKRD36BP1 AP1M1 AQP1 AQP5 ARID5A ARMC7 ARSI ASMTL ATPAF2 AVPI1 BAHD1 BARD1 BCAS2 BEX2 BMS1P5 BYSL C10orf62 C11orf87 C14orf105 C19orf57 C19orf66 C19orf73 C1orf109 C1orf216 C20orf195 C22orf46 C5orf60 C6orf165 C6orf226 C8orf48 CA6 CARD9 CATIP CBX8 CCDC112 CCDC120 CCDC146 CCDC185 CCDC26 CCDC93 CCER1 CCHCR1 CCNG1 CD33 CDC20B CDK18 CDK5R1 CELA2B CEP57 CEP57L1 CHCHD2 CHCHD3 CHIC2 CLEC18A CNTF COL8A1 COMT COX5A CREB5 CTSZ CWF19L2 CYCS CYTH4 DAAM2 DCDC2B DCX DDX6 DLGAP2 DMRT3 DOCK2 DOCK8 DTNB EIF4E2 EXOC3-AS1 FAM107A FAM124B FAM214A FAM27E3 FAM64A FAM71C FAM74A4 FAM90A1 FARS2 FASLG FBF1 FBXL18 FBXO34 FBXW5 FKBP1B FOXB1 FRG1 GATA2 GATAD2A GEM GFOD1 GGN GLIDR GNAI2 GNG5 GOLGA6L2 GPATCH2L GTF3C5 GUCD1 HAUS1 HBA2 HBZ HCK HDAC4 HGS HOXA1 HSPA12B HSPD1 ING5 INPP5D IQUB ISCU ITGB5 JOSD1 KAT5 KCTD9 KIFC3 KLHL38 KPNA2 KRT2 KRT20 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LAGE3 LCE3E LENG1 LIMS2 LIN37 LINC00636 LINC01588 LMF2 LMO1 LMO2 LMO4 LOC149950 LRCH4 MAB21L2 MAGOHB MAPKBP1 MARK4 MED8 METTL17 MFAP1 MOB3C MOS MRPL11 MTA1 MXI1 NAB2 NAPRT NDEL1 NEK6 NFKBID NINJ1 NPBWR2 NPPB NR1D2 NXF1 OPCML OTUB2 PDLIM5 PGLS PHF21A PIGS PIN1 PKD2 POLDIP3 POLL POM121L8P POP5 PPP1R18 PRAM1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMC5 PTGER3 PTPMT1 PXMP2 QPRT RAB3IL1 RAB3IP RAC1 RASSF5 RBM41 RCOR3 RECK RNF213 RPL11 RSPH14 RTP5 RWDD2B SCOC SEMA4C SETD5 SH2D4A SHC3 SIRPA SLC25A10 SLIRP SLU7 SMARCE1 SMCO4 SNAI1 SNHG11 SNRPB SNW1 SPATA24 SPEF1 SPG7 SRSF2 SSX2 SSX2IP SYT6 TAPBPL TBC1D16 TBC1D22B TCEA2 TCEB3 TCHP THAP7 TIE1 TMEM231 TMEM241 TMSB4X TNIP3 TNNT1 TRAF4 TRIM42 TROAP TRPV6 TSC22D4 TSGA10IP TSHZ3 TTC23 TTC25 TTLL10 TXLNA TXN2 TXNDC5 TYK2 TYRO3 UACA UBASH3A UCMA USHBP1 USP2 USP21 UTP14C UTP23 UXT WDR25 WT1 WT1-AS ZBTB16 ZBTB24 ZBTB38 ZC2HC1C ZFHX3 ZFP2 ZFP69B ZFYVE21 ZFYVE26 ZGPAT ZMAT2 ZNF101 ZNF124 ZNF138 ZNF165 ZNF20 ZNF202 ZNF230 ZNF250 ZNF26 ZNF266 ZNF286A ZNF317 ZNF329 ZNF337 ZNF417 ZNF439 ZNF446 ZNF488 ZNF490 ZNF564 ZNF569 ZNF581 ZNF587 ZNF625 ZNF655 ZNF697 ZNF702P ZNF792 ZNF844 ZNRF2P1 ZSCAN21
Entrez ID		3849	125115
HPRD ID		02560	08304
Ensembl ID		ENSG00000172867	ENSG00000204889
Uniprot IDs		P35908	Q6A162
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta3 Production Anatomical Structure Development Evasion Or Tolerance Of Host Defenses By Virus Developmental Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Epithelium Development Regulation Of Extracellular Matrix Assembly Organ Development Primary MiRNA Processing Epidermis Development Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Transdifferentiation Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Alkaline Phosphatase Activity Paraxial Mesoderm Morphogenesis Nodal Signaling Pathway Tissue Development Positive Regulation Of Transforming Growth Factor Beta Production Embryonic Organ Development Tongue Morphogenesis System Development Regulation Of Osteoblast Proliferation In Utero Embryonic Development Embryonic Foregut Morphogenesis Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Production Of MiRNAs Involved In Gene Silencing By MiRNA Foregut Morphogenesis Modulation By Virus Of Host Morphology Or Physiology Paraxial Mesoderm Development Regulation Of Catenin Import Into Nucleus Epithelial Cell Differentiation Thyroid Gland Development Osteoblast Development Viral Process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Chondrocyte Differentiation Pericardium Development Positive Regulation Of Phosphatase Activity Positive Regulation Of Positive Chemotaxis Sensory Organ Development Positive Regulation Of Interleukin-1 Production Signal Transduction Involved In Regulation Of Gene Expression Activin Receptor Signaling Pathway Lens Fiber Cell Differentiation Multicellular Organismal Development	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Defense Response To Virus By Virus Regulation Of Cell Death Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Apoptotic Process Bicarbonate Transport Cell Death Death Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Intermediate Filament Cytoskeleton Organization Cytoskeleton Organization Microtubule Organizing Center Organization Positive Regulation Of Cellular Protein Metabolic Process Intermediate Filament-based Process Organelle Organization Multicellular Organismal Development
Tagcloud ?		agn193109 am580 cd2081 cd3106 cd336 cd367 crabpii dermis epidermis epidermized k10 k13 k2 k4 keratin keratinization keratinocytes keratins krt1 krt10 krt13 krt4 learn looking pan raralpha reciprocal suprabasal
Tagcloud (Difference) ?		agn193109 am580 cd2081 cd3106 cd336 cd367 crabpii dermis epidermis epidermized k10 k13 k2 k4 keratin keratinization keratinocytes keratins krt1 krt10 krt13 krt4 learn looking pan raralpha reciprocal suprabasal
Tagcloud (Intersection) ?