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KRT40 and COL8A1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRT40
COL8A1
Gene Name
keratin 40, type I
collagen, type VIII, alpha 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intermediate Filament
Extracellular Region
Collagen Type VIII Trimer
Endoplasmic Reticulum Lumen
Extracellular Matrix
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Structural Molecule Activity
Biological Process
Angiogenesis
Cell Adhesion
Positive Regulation Of Cell-substrate Adhesion
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Endodermal Cell Differentiation
Camera-type Eye Morphogenesis
Epithelial Cell Proliferation
Pathways
Collagen formation
Collagen degradation
Integrin cell surface interactions
Collagen biosynthesis and modifying enzymes
Degradation of the extracellular matrix
Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Age-related macular degeneration (
20385826
23455636
)
Protein-Protein Interactions
313 interactors:
ADAMTSL3
AEN
AES
AKAP17A
ALDH3B1
ALS2CR11
ANKRD36BP1
AP1M1
AQP1
AQP5
ARID5A
ARMC7
ARSI
ASMTL
ATPAF2
AVPI1
BAHD1
BARD1
BCAS2
BEX2
BMS1P5
BYSL
C10orf62
C11orf87
C14orf105
C19orf57
C19orf66
C19orf73
C1orf109
C1orf216
C20orf195
C22orf46
C5orf60
C6orf165
C6orf226
C8orf48
CA6
CARD9
CATIP
CBX8
CCDC112
CCDC120
CCDC146
CCDC185
CCDC26
CCDC93
CCER1
CCHCR1
CCNG1
CD33
CDC20B
CDK18
CDK5R1
CELA2B
CEP57
CEP57L1
CHCHD2
CHCHD3
CHIC2
CLEC18A
CNTF
COL8A1
COMT
COX5A
CREB5
CTSZ
CWF19L2
CYCS
CYTH4
DAAM2
DCDC2B
DCX
DDX6
DLGAP2
DMRT3
DOCK2
DOCK8
DTNB
EIF4E2
EXOC3-AS1
FAM107A
FAM124B
FAM214A
FAM27E3
FAM64A
FAM71C
FAM74A4
FAM90A1
FARS2
FASLG
FBF1
FBXL18
FBXO34
FBXW5
FKBP1B
FOXB1
FRG1
GATA2
GATAD2A
GEM
GFOD1
GGN
GLIDR
GNAI2
GNG5
GOLGA6L2
GPATCH2L
GTF3C5
GUCD1
HAUS1
HBA2
HBZ
HCK
HDAC4
HGS
HOXA1
HSPA12B
HSPD1
ING5
INPP5D
IQUB
ISCU
ITGB5
JOSD1
KAT5
KCTD9
KIFC3
KLHL38
KPNA2
KRT2
KRT20
KRT4
KRT5
KRT6A
KRT6C
KRT71
KRT72
KRT8
KRT81
LAGE3
LCE3E
LENG1
LIMS2
LIN37
LINC00636
LINC01588
LMF2
LMO1
LMO2
LMO4
LOC149950
LRCH4
MAB21L2
MAGOHB
MAPKBP1
MARK4
MED8
METTL17
MFAP1
MOB3C
MOS
MRPL11
MTA1
MXI1
NAB2
NAPRT
NDEL1
NEK6
NFKBID
NINJ1
NPBWR2
NPPB
NR1D2
NXF1
OPCML
OTUB2
PDLIM5
PGLS
PHF21A
PIGS
PIN1
PKD2
POLDIP3
POLL
POM121L8P
POP5
PPP1R18
PRAM1
PRKAA1
PRKAB2
PRPF31
PSMA1
PSMC5
PTGER3
PTPMT1
PXMP2
QPRT
RAB3IL1
RAB3IP
RAC1
RASSF5
RBM41
RCOR3
RECK
RNF213
RPL11
RSPH14
RTP5
RWDD2B
SCOC
SEMA4C
SETD5
SH2D4A
SHC3
SIRPA
SLC25A10
SLIRP
SLU7
SMARCE1
SMCO4
SNAI1
SNHG11
SNRPB
SNW1
SPATA24
SPEF1
SPG7
SRSF2
SSX2
SSX2IP
SYT6
TAPBPL
TBC1D16
TBC1D22B
TCEA2
TCEB3
TCHP
THAP7
TIE1
TMEM231
TMEM241
TMSB4X
TNIP3
TNNT1
TRAF4
TRIM42
TROAP
TRPV6
TSC22D4
TSGA10IP
TSHZ3
TTC23
TTC25
TTLL10
TXLNA
TXN2
TXNDC5
TYK2
TYRO3
UACA
UBASH3A
UCMA
USHBP1
USP2
USP21
UTP14C
UTP23
UXT
WDR25
WT1
WT1-AS
ZBTB16
ZBTB24
ZBTB38
ZC2HC1C
ZFHX3
ZFP2
ZFP69B
ZFYVE21
ZFYVE26
ZGPAT
ZMAT2
ZNF101
ZNF124
ZNF138
ZNF165
ZNF20
ZNF202
ZNF230
ZNF250
ZNF26
ZNF266
ZNF286A
ZNF317
ZNF329
ZNF337
ZNF417
ZNF439
ZNF446
ZNF488
ZNF490
ZNF564
ZNF569
ZNF581
ZNF587
ZNF625
ZNF655
ZNF697
ZNF702P
ZNF792
ZNF844
ZNRF2P1
ZSCAN21
20 interactors:
ADAMTSL4
COL8A2
CREB5
EFEMP2
INCA1
ITGA1
ITGA2
KLHL12
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP26-1
KRTAP4-12
KRTAP9-2
NOTCH2NL
REL
SP4
UBQLN4
VAC14
Entrez ID
125115
1295
HPRD ID
08304
00372
Ensembl ID
ENSG00000204889
ENSG00000144810
Uniprot IDs
Q6A162
P27658
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Cellular Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Process
Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Defense Response To Virus By Virus
Regulation Of Cell Death
Regulation Of Protein Metabolic Process
Anatomical Structure Development
Regulation Of Apoptotic Process
Bicarbonate Transport
Cell Death
Death
Centrosome Organization
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Intermediate Filament Cytoskeleton Organization
Cytoskeleton Organization
Microtubule Organizing Center Organization
Positive Regulation Of Cellular Protein Metabolic Process
Intermediate Filament-based Process
Organelle Organization
Multicellular Organismal Development
Extracellular Matrix Organization
Extracellular Structure Organization
Positive Regulation Of Phosphatase Activity
Positive Regulation Of Dephosphorylation
Positive Regulation Of Collagen Binding
Tagcloud
?
bladder
carcinogenic
deregulation
elucidates
emodin
epigenetic
epigenetics
fabp4
h3k27
h3k27me3
h3s10
hbp17
inc
periodicals
ph3ser10
rational
repressed
restore
reverses
reversing
rgs4
situations
specialized
timp3
urb
viii
warrants
wiley
wnt5b
Tagcloud (Difference)
?
bladder
carcinogenic
deregulation
elucidates
emodin
epigenetic
epigenetics
fabp4
h3k27
h3k27me3
h3s10
hbp17
inc
periodicals
ph3ser10
rational
repressed
restore
reverses
reversing
rgs4
situations
specialized
timp3
urb
viii
warrants
wiley
wnt5b
Tagcloud (Intersection)
?