MSL1 and PAF1

Number of citations of the paper that reports this interaction (PMID 24837678)
0

Data Source:
BioGRID (pull down)

		MSL1	PAF1
Gene Name		male-specific lethal 1 homolog (Drosophila)	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm MSL Complex	Cdc73/Paf1 Complex
	Molecular Function		RNA Polymerase II Core Binding Chromatin Binding Protein Binding
	Biological Process	Chromatin Organization Histone H4-K16 Acetylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Transcription, DNA-templated MRNA Polyadenylation Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipopolysaccharide
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: CRKL FCHSD2 HIST2H2BE HORMAD1 KAT8 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3	12 interactors: FXR2 HIST1H1C HIST1H3A KAT8 KMT2A LEO1 MLLT1 MSL1 MSL2 MSL3 RNF20 TCEA1
Entrez ID		339287	54623
HPRD ID		19425	10140
Ensembl ID		ENSG00000188895	ENSG00000006712
Uniprot IDs		B3KWR7 J3KSZ8 Q68DK7	M0QX35 Q8N7H5
PDB IDs		4B7Y 4B86 4DNC	4M6T
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Protein Monoubiquitination Histone H2B Ubiquitination Chromatin Modification Histone Monoubiquitination Histone Ubiquitination Histone Modification Organelle Organization Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Protein Acetylation Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Import Intracellular Transport Of Virus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Histone Methylation Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Protein Ubiquitination RNA Metabolic Process Cellular Protein Modification Process Regulation Of Histone Methylation Histone H4 Acetylation Protein Modification By Small Protein Conjugation Regulation Of Homologous Chromosome Segregation Positive Regulation Of Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Histone Modification Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Meiotic Recombination Checkpoint Positive Regulation Of Vitamin D Receptor Signaling Pathway	Histone H4-K16 Acetylation Chromatin Organization Histone H4 Acetylation Chromosome Organization Histone Modification Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Chromatin Modification Peptidyl-lysine Modification Organelle Organization Histone H2B Ubiquitination Histone Monoubiquitination Peptidyl-amino Acid Modification Regulation Of Gene Expression Histone Ubiquitination Positive Regulation Of Histone Methylation Protein Monoubiquitination Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Histone Methylation Regulation Of DNA-templated Transcription, Elongation Cellular Protein Modification Process Regulation Of RNA Metabolic Process DNA Methylation Transcription, DNA-templated Positive Regulation Of Cellular Response To Drug Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression RNA Biosynthetic Process Positive Regulation Of Histone Modification Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process DNA Modification Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Protein Metabolic Process Nucleosome Assembly Regulation Of Histone Modification Chromatin Assembly Nucleosome Organization Regulation Of Metabolic Process Regulation Of Response To Drug
Tagcloud ?		alters aspect comprise correlating cryptic exonic h2b h2bk123ub1 h3k36me3 htb intragenic intron intronic introns k123r lea1 lethality marks monoubiquitylation orfs packaging postulated saccharomyces snrnp splicing talk transcribed trimethylation u2	ablates ada2 ap2 apicomplexa apicomplexan dd ddhagcn5b destabilization dispensable e703g gcn5a gcn5b gondii indispensable invertebrates kat kats leo1 lytic parasite parasites phylum possessing proteomics protozoan redundant rrm tfiid toxoplasma
Tagcloud (Difference) ?		alters aspect comprise correlating cryptic exonic h2b h2bk123ub1 h3k36me3 htb intragenic intron intronic introns k123r lea1 lethality marks monoubiquitylation orfs packaging postulated saccharomyces snrnp splicing talk transcribed trimethylation u2	ablates ada2 ap2 apicomplexa apicomplexan dd ddhagcn5b destabilization dispensable e703g gcn5a gcn5b gondii indispensable invertebrates kat kats leo1 lytic parasite parasites phylum possessing proteomics protozoan redundant rrm tfiid toxoplasma
Tagcloud (Intersection) ?