HIST1H1A and CTCFL

Number of citations of the paper that reports this interaction (PMID 17048991)
45

Data Source:
BioGRID (far western blotting, pull down)

		HIST1H1A	CTCFL
Gene Name		histone cluster 1, H1a	CCCTC-binding factor (zinc finger protein)-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nuclear Chromatin Nuclear Euchromatin	Nucleus Cytoplasm
	Molecular Function	Protein Binding Chromatin DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Protein Binding Histone Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Nucleosome Assembly Spermatogenesis	Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Cell Cycle Positive Regulation Of Gene Expression Histone Methylation DNA Methylation Involved In Gamete Generation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Histone H3-K4 Methylation
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Response to statin therapy ( 20339536) Type 2 diabetes ( 23300278)
Protein-Protein Interactions		45 interactors: AEBP2 CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L4 NASP PARP1 PARP3 PELP1 PKN1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 SUZ12 TERF1 TERF2IP TLK1 WHSC1L1	7 interactors: BAG6 BRCA1 HIST1H1A HIST1H3A HIST2H2AC PRMT7 ZDHHC17
Entrez ID		3024	140690
HPRD ID		00820	09512
Ensembl ID		ENSG00000124610	ENSG00000124092
Uniprot IDs		Q02539	A6XGM0 A6XGM9 A6XGN2 A6XGN4 Q8NI51
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromosome Organization Cell Cycle Chromatin Organization Chromatin Modification Regulation Of Cell Cycle Organelle Organization Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Histone Modification Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Nitrogen Compound Metabolic Process Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Protein Phosphorylation Regulation Of Mitotic Cell Cycle Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle DNA Metabolic Process Cellular Response To Stress Response To Stress Histone Phosphorylation Regulation Of Catalytic Activity Peptidyl-amino Acid Modification Cellular Metabolic Process Regulation Of Cell Cycle Process Phosphorylation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression, Epigenetic	Regulation Of Gene Expression By Genetic Imprinting Regulation Of Gene Expression, Epigenetic Genetic Imprinting Chromatin Organization Chromosome Organization DNA Methylation DNA Modification Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Signal Transduction By P53 Class Mediator Nucleosome Assembly Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Positive Regulation Of Histone H3-K9 Acetylation Cellular Macromolecular Complex Assembly Gamete Generation Chromatin Assembly Organelle Organization Nucleosome Organization Chromatin Assembly Or Disassembly Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Protein-DNA Complex Assembly Sexual Reproduction Cellular Component Assembly Multicellular Organismal Reproductive Process DNA Packaging Intrinsic Apoptotic Signaling Pathway Multicellular Organism Reproduction Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Chromosome Segregation Dosage Compensation By Inactivation Of X Chromosome Tail-anchored Membrane Protein Insertion Into ER Membrane Protein K6-linked Ubiquitination Protein Insertion Into ER Membrane Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Reproduction DNA Metabolic Process Histone H4-R3 Methylation DNA Replication-dependent Nucleosome Assembly DNA Conformation Change Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Peptidyl-arginine N-methylation Regulation Of Histone H4 Acetylation
Tagcloud ?			boundaries causal compact demethylation depleted finger functionally generating h3k27me3 inactive incorporation inducer insulator insulators iptg lac laci mark modification neighbouring ones preceded removes requirement separate spreading thereby variant
Tagcloud (Difference) ?			boundaries causal compact demethylation depleted finger functionally generating h3k27me3 inactive incorporation inducer insulator insulators iptg lac laci mark modification neighbouring ones preceded removes requirement separate spreading thereby variant
Tagcloud (Intersection) ?