GFER and PLEKHF2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GFER	PLEKHF2
Gene Name		growth factor, augmenter of liver regeneration	pleckstrin homology domain containing, family F (with FYVE domain) member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Intermembrane Space	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Protein Binding Growth Factor Activity Protein Disulfide Oxidoreductase Activity Thiol Oxidase Activity Flavin Adenine Dinucleotide Binding	Protein Binding Metal Ion Binding
	Biological Process	Protein Targeting To Mitochondrion Cellular Protein Metabolic Process Oxidation-reduction Process	Protein Transport
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS			Radiation response ( 20923822)
Protein-Protein Interactions		7 interactors: ASCC2 BNIPL COPS2 COPS5 PLEKHF2 SMAD2 TXN	52 interactors: ACY3 AIMP2 APP APPL1 BEND7 BLOC1S6 BSCL2 CCDC85B CEP44 CHIC2 DTX2 DUT FBXO28 FHL3 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NONO NPM2 PRKAR1A PRPSAP1 RABAC1 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SDPR SEPT2 SEPT6 SETBP1 SFN SPEF1 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z ZNF250 ZNF263 ZNF398
Entrez ID		2671	79666
HPRD ID		02954	15147
Ensembl ID		ENSG00000127554	ENSG00000175895
Uniprot IDs		P55789	Q9H8W4
PDB IDs		3MBG 3O55 3TK0 3U2L 3U2M 3U5S
Enriched GO Terms of Interacting Partners?		Cullin Deneddylation Protein Deneddylation Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Removal Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry RNA Metabolic Process Regulation Of Growth Rate Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Exosomal Secretion Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Primary MiRNA Processing Negative Regulation Of Protein Export From Nucleus Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Binding Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death SMAD Protein Complex Assembly Nucleobase-containing Compound Metabolic Process Regulation Of Hydrogen Peroxide-induced Cell Death Paraxial Mesoderm Morphogenesis Nodal Signaling Pathway Nucleobase-containing Small Molecule Interconversion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Regulation Of Protein Import Into Nucleus, Translocation Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis Foregut Morphogenesis	Apoptotic Process Programmed Cell Death Cell Death Death Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		acting alr apoptotic augmenter behaviour caspase clusterin complementary encodes erv1 glioma hepatectomized integrity lethal modulates named neuroblastoma normoxic oxidase peroxide preserve ralr regenerating regeneration ros shed sulfhydryl supports t98g	abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Difference) ?		acting alr apoptotic augmenter behaviour caspase clusterin complementary encodes erv1 glioma hepatectomized integrity lethal modulates named neuroblastoma normoxic oxidase peroxide preserve ralr regenerating regeneration ros shed sulfhydryl supports t98g	abnormally attempt cargo colocalized concert depleted dextran discover eea1 effectors egf endosomal endosome endosomes enlarged facilitating fyve interactor microdomains mtmr4 orchestrates phafin2 proteome ptdins3p px recruiting screen termination tethering
Tagcloud (Intersection) ?