AATF and SS18L1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		AATF	SS18L1
Gene Name		apoptosis antagonizing transcription factor	synovial sarcoma translocation gene on chromosome 18-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Golgi Apparatus Centrosome Focal Adhesion	Kinetochore Condensed Chromosome Kinetochore Condensed Nuclear Chromosome, Centromeric Region Nucleus Nuclear Body NBAF Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Leucine Zipper Domain Binding Poly(A) RNA Binding Tau Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Reactive Oxygen Species Metabolic Process	Transcription, DNA-templated Dendrite Development Chromatin Modification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Dendrite Morphogenesis
Pathways		Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		26 interactors: ATM ATR CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MPP6 NEDD4L NGDN PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468	30 interactors: AATF ANKRD22 ATF3 BRD1 CREBBP CSTF2 CTAGE5 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 LGALS3 MAPK1IP1L MED30 NR1H3 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC STAT3 TAF9B TCF7
Entrez ID		26574	26039
HPRD ID		12236	09398
Ensembl ID		ENSG00000108270	ENSG00000184402
Uniprot IDs		Q9NY61	B4DSR7 O75177
PDB IDs
Enriched GO Terms of Interacting Partners?		Replicative Senescence Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression DNA Damage Induced Protein Phosphorylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Biosynthetic Process Cell Aging Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Apoptotic Signaling Pathway RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Protein Catabolic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cell Cycle Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Programmed Cell Death Negative Regulation Of Cell Cycle Cell Cycle Process Cell Death Death Regulation Of Mitotic Nuclear Division Response To Abiotic Stimulus Cell Differentiation Regulation Of Cell Proliferation Gene Expression Developmental Process Transforming Growth Factor Beta Receptor Signaling Pathway	RNA Metabolic Process Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cell Differentiation Regulation Of Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Epithelium Development RNA Processing Histone Modification N-terminal Peptidyl-lysine Acetylation DNA-templated Transcription, Initiation Gene Silencing Cellular Metabolic Process Negative Regulation Of Cell Death Histone Acetylation Peptidyl-lysine Modification Tissue Development Internal Peptidyl-lysine Acetylation
Tagcloud ?		accuracy balb behavioral biomarker circadian comprising cooperativity crucial directed encoded exists explore fact forensic governs hence investigation keeping metabolism microrna mortem pmi reasonably rhythm rhythmicity rnome turn unambiguously view	acetyl allantoic brg1 chorio crest embryos ini1 interbreeding knockout lethal linearities peroxisome phenotype placental pparbp proliferator recessive resembles sarcoma snf ssxt structurally swi synergistically synovial syt transferase vascularization
Tagcloud (Difference) ?		accuracy balb behavioral biomarker circadian comprising cooperativity crucial directed encoded exists explore fact forensic governs hence investigation keeping metabolism microrna mortem pmi reasonably rhythm rhythmicity rnome turn unambiguously view	acetyl allantoic brg1 chorio crest embryos ini1 interbreeding knockout lethal linearities peroxisome phenotype placental pparbp proliferator recessive resembles sarcoma snf ssxt structurally swi synergistically synovial syt transferase vascularization
Tagcloud (Intersection) ?