AATF and MPHOSPH6

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		AATF	MPHOSPH6
Gene Name		apoptosis antagonizing transcription factor	M-phase phosphoprotein 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Golgi Apparatus Centrosome Focal Adhesion	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleolus Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Leucine Zipper Domain Binding Poly(A) RNA Binding Tau Protein Binding	RNA Binding Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Reactive Oxygen Species Metabolic Process	Maturation Of 5.8S RRNA
Pathways		Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		26 interactors: ATM ATR CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MPP6 NEDD4L NGDN PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468	24 interactors: AATF APLP1 ARHGAP18 C14orf1 DNM2 DYNLRB1 EIF3G EXOSC10 FTL GDF9 KNSTRN LRIF1 NUPR1 PARN RBM48 RPS20 SKIV2L2 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1
Entrez ID		26574	10200
HPRD ID		12236	16111
Ensembl ID		ENSG00000108270	ENSG00000135698
Uniprot IDs		Q9NY61	Q99547
PDB IDs
Enriched GO Terms of Interacting Partners?		Replicative Senescence Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression DNA Damage Induced Protein Phosphorylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Biosynthetic Process Cell Aging Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Apoptotic Signaling Pathway RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Protein Catabolic Process Biosynthetic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Cell Cycle Checkpoint Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Apoptotic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Programmed Cell Death Negative Regulation Of Cell Cycle Cell Cycle Process Cell Death Death Regulation Of Mitotic Nuclear Division Response To Abiotic Stimulus Cell Differentiation Regulation Of Cell Proliferation Gene Expression Developmental Process Transforming Growth Factor Beta Receptor Signaling Pathway	Gene Expression RNA Metabolic Process Regulation Of Female Gonad Development Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Metabolic Process Maturation Of 5.8S RRNA Positive Regulation Of Protein Oligomerization Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Endocytosis Regulation Of Protein Oligomerization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic Cell Cycle Process Nuclear-transcribed MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Negative Regulation Of Cell Growth MRNA Catabolic Process Negative Regulation Of Fibroblast Proliferation Nitrogen Compound Metabolic Process Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Cell Division Regulation Of Gene Expression RNA Catabolic Process Ribosome Biogenesis Regulation Of Metabolic Process Mitotic Cytokinesis Negative Regulation Of Reactive Oxygen Species Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Clathrin-mediated Endocytosis Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Membrane Organization Growth Negative Regulation Of Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Growth Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Processing Regulation Of Apoptotic Process Negative Regulation Of Macromitophagy Negative Regulation Of Membrane Tubulation Lipid Tube Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Negative Regulation Of Caveolin-mediated Endocytosis Oocyte Growth
Tagcloud ?		accuracy balb behavioral biomarker circadian comprising cooperativity crucial directed encoded exists explore fact forensic governs hence investigation keeping metabolism microrna mortem pmi reasonably rhythm rhythmicity rnome turn unambiguously view
Tagcloud (Difference) ?		accuracy balb behavioral biomarker circadian comprising cooperativity crucial directed encoded exists explore fact forensic governs hence investigation keeping metabolism microrna mortem pmi reasonably rhythm rhythmicity rnome turn unambiguously view
Tagcloud (Intersection) ?