FLNA and CMIP

Number of citations of the paper that reports this interaction (PMID 15128042)
5

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		FLNA	CMIP
Gene Name		filamin A, alpha	c-Maf inducing protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Trans-Golgi Network Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Cortical Cytoskeleton Myb Complex Neuronal Cell Body Dendritic Shaft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Apical Dendrite	Nucleus Cytoplasm
	Molecular Function	Glycoprotein Binding Signal Transducer Activity Protein Kinase C Binding Protein Binding Transcription Factor Binding Rho GTPase Binding Ral GTPase Binding Small GTPase Binding Mu-type Opioid Receptor Binding Fc-gamma Receptor I Complex Binding Protein Homodimerization Activity Poly(A) RNA Binding SMAD Binding Rac GTPase Binding Actin Filament Binding	Protein Binding
	Biological Process	Epithelial To Mesenchymal Transition Platelet Degranulation Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Blood Coagulation Platelet Activation Actin Cytoskeleton Reorganization Cell Junction Assembly Protein Localization To Cell Surface Negative Regulation Of Protein Catabolic Process Cilium Assembly MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription Factor Import Into Nucleus Receptor Clustering Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Early Endosome To Late Endosome Transport Establishment Of Protein Localization Protein Stabilization Cytoplasmic Sequestering Of Protein Actin Crosslink Formation Platelet Aggregation Mitotic Spindle Assembly
Pathways		Cell junction organization GP1b-IX-V activation signalling Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Cell-extracellular matrix interactions
Drugs
Diseases
GWAS			Adiponectin levels ( 22479202) Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) HDL cholesterol ( 20686565) Menarche (age at onset) ( 23667675) Type 2 diabetes ( 22158537)
Protein-Protein Interactions		82 interactors: ADAMTSL4 APC AR ARHGAP24 ARRB1 ARRB2 ASB2 BRCA2 CALCR CAMK2G CASR CAV1 CCNB1 CDC42 CEACAM1 CMIP DCN DRD1 DRD2 DRD3 ERBB3 F3 FABP1 FAM101A FBLIM1 FILIP1 FLNB FURIN GP1BA GRIK1 GRIK3 GRM4 GRM5 GRM7 GRM8 HNRNPD HSPB7 ITGB1 ITGB3 ITGB5 ITGB6 ITGB7 KCNE4 KCNJ2 KLHL12 LGALS14 LMNA MAP2K4 MAPK14 MTNR1A MTNR1B MYOT NPHP1 OPRM1 PAK1 PCBP2 PRKCA PSEN1 PSEN2 RAC1 RALA REL RHOA SELE SH2B3 SHBG SIGLEC10 SMAD3 SMAD5 SRC SVIL SYNPO2 TCF4 TLR10 TNIP2 TRAF2 TRIM55 TRIO TTN USP19 VHL YWHAG	1 interactors: FLNA
Entrez ID		2316	80790
HPRD ID		02060	10839
Ensembl ID		ENSG00000196924	ENSG00000153815
Uniprot IDs		P21333 Q60FE5 Q6NXF2	Q8IY22
PDB IDs		2AAV 2BP3 2BRQ 2J3S 2JF1 2K3T 2K7P 2K7Q 2W0P 2WFN 3CNK 3HOC 3HOP 3HOR 3ISW 3RGH
Enriched GO Terms of Interacting Partners?		Signal Transduction Cellular Response To Stimulus Signaling Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Response To Stress Regulation Of Phosphorus Metabolic Process Wound Healing Response To Wounding Regulation Of Signaling Positive Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Metabolic Process Response To External Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity Apoptotic Process Response To Abiotic Stimulus Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Cellular Process Positive Regulation Of Catalytic Activity Negative Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Phosphorylation Tissue Development Blood Coagulation Hemostasis Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Localization G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Regulation Of Signal Transduction Regulation Of Protein Kinase Activity Multicellular Organismal Development System Development Cellular Response To Organic Substance Regulation Of Apoptotic Process Developmental Process	Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway MRNA Transcription From RNA Polymerase II Promoter MRNA Transcription Protein Localization To Cell Surface Mitotic Spindle Assembly Early Endosome To Late Endosome Transport Actin Crosslink Formation Cytoplasmic Sequestering Of Protein Dopamine Receptor Signaling Pathway Platelet Aggregation Positive Regulation Of Transcription Factor Import Into Nucleus Mitotic Spindle Organization Receptor Clustering Epithelial To Mesenchymal Transition Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Actin Cytoskeleton Reorganization Platelet Degranulation Spindle Assembly Regulation Of Transcription Factor Import Into Nucleus Protein Stabilization Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Mesenchymal Cell Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Catabolic Process Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Spindle Organization Mesenchymal Cell Differentiation Regulation Of Protein Stability Maintenance Of Protein Location In Cell G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Maintenance Of Protein Location Maintenance Of Location In Cell Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Cilium Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Protein Transport Platelet Activation Cilium Organization Regulation Of Protein Localization To Nucleus Cell Junction Assembly Mesenchyme Development Endosomal Transport Regulation Of Nucleocytoplasmic Transport Cilium Morphogenesis Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intracellular Transport Stem Cell Development
Tagcloud ?		actin acts aggregation bilateral calcineurin cortical cytoskeleton defects downregulation heterotopia isoforms knockdown lateral lining linking malformation migration periventricular ph prevented progenitor radial rcan1 rearrangement regulators shrna underlie upstream ventricles	absorbent anions benzoate beverage citrate clean conducting disposable electro electrochemically film flavoring graph hplc imprinted microextraction molecularly nanostructure optimised polypyrrole salicylate sorbate sorbent spectrophotometric spectrophotometry spme synthesised template vanilla
Tagcloud (Difference) ?		actin acts aggregation bilateral calcineurin cortical cytoskeleton defects downregulation heterotopia isoforms knockdown lateral lining linking malformation migration periventricular ph prevented progenitor radial rcan1 rearrangement regulators shrna underlie upstream ventricles	absorbent anions benzoate beverage citrate clean conducting disposable electro electrochemically film flavoring graph hplc imprinted microextraction molecularly nanostructure optimised polypyrrole salicylate sorbate sorbent spectrophotometric spectrophotometry spme synthesised template vanilla
Tagcloud (Intersection) ?