IKZF3 and MAGOHB

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF3	MAGOHB
Gene Name		IKAROS family zinc finger 3 (Aiolos)	mago-nashi homolog B (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation	MRNA Processing RNA Splicing MRNA Transport
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT	20 interactors: AES AMOTL2 CALCOCO2 CCDC102B GOLGA2 HMG20A IKZF3 KRT40 MID2 RBM8A RBMX REL RUNDC3A TCF4 TERF2 TERF2IP TRIM42 YWHAG ZNF250 ZNF398
Entrez ID		22806	55110
HPRD ID		05869	08544
Ensembl ID
Uniprot IDs		Q9UKT9	F5H6P7 Q96A72
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Protection From Non-homologous End Joining At Telomere Negative Regulation Of Cellular Metabolic Process Telomere Capping Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Protein Localization To Chromosome, Telomeric Region RNA Metabolic Process Regulation Of Metabolic Process Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Gene Expression Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Telomere Maintenance Biosynthetic Process Regulation Of Gene Expression RNA-dependent DNA Replication Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Binding Regulation Of Transcription, DNA-templated Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Gene Expression Protein Localization To Chromosome Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Regulation Of RNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Nitrogen Compound Metabolic Process Protein Localization To Organelle Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Protein Binding Regulation Of Binding Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of RNA Biosynthetic Process Wnt Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Response To Cytokine Telomere Maintenance Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Tagcloud ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?