ETS1 and ARL6IP4

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		ETS1	ARL6IP4
Gene Name		v-ets avian erythroblastosis virus E26 oncogene homolog 1	ADP-ribosylation factor-like 6 interacting protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Intercellular Bridge	Nucleus Nucleolus Nuclear Speck
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Histone Acetyltransferase Binding Sequence-specific DNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Response To Hypoxia Transcription From RNA Polymerase II Promoter Immune Response Female Pregnancy Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Mechanical Stimulus Positive Regulation Of Endothelial Cell Migration Regulation Of Extracellular Matrix Disassembly Hypothalamus Development Pituitary Gland Development PML Body Organization Response To Estradiol Response To Laminar Fluid Shear Stress Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Regulation Of Angiogenesis Positive Regulation Of Angiogenesis Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Antibiotic Cell Motility Positive Regulation Of Cellular Component Movement Angiogenesis Involved In Wound Healing Cellular Response To Hydrogen Peroxide Response To Interleukin-1	MRNA Processing RNA Splicing
Pathways		Cellular Senescence Oncogene Induced Senescence
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Obesity-related traits ( 23251661) Rheumatoid arthritis ( 22446963) Systemic lupus erythematosus ( 23273568 20169177 19838193)
Protein-Protein Interactions		47 interactors: APLP2 APP ARID4B ARL6IP4 ATF2 BRCA1 C17orf62 CAMK2A CAMK2B CREBBP DAXX EIF5B EP300 ETS2 FOS GATA3 HTATIP2 JUN MAF MAPK1 MAPK3 MAPK7 MED23 MEIS1 NCL NCOR1 NFKB1 NR3C1 PAX5 POU1F1 RBBP6 RFWD2 RPL13A RUNX1 RUNX1T1 RUNX2 SMAD3 SP1 SP100 SPI1 SRA1 SRC SRSF11 STAT5B STAT6 TDP2 UBE2I	11 interactors: ARL6 CSNK2A1 ETS1 FOS IKBKG RBM39 RNF41 SRPK1 SRPK2 SRSF11 THAP1
Entrez ID		2113	51329
HPRD ID		01260	09640
Ensembl ID		ENSG00000134954	ENSG00000182196
Uniprot IDs		A8K725 B4DW78 P14921	B3V0L0 B3V0L1 Q66PJ3
PDB IDs		1GVJ 2NNY 2STT 2STW 3MFK 3RI4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Gene Expression RNA Metabolic Process Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Immune System Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Innate Immune Response Biosynthetic Process Developmental Process Cell Differentiation Cellular Metabolic Process Cellular Response To Organic Substance Immune Response Cellular Response To Growth Factor Stimulus Multicellular Organismal Development Response To Growth Factor System Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Abiotic Stimulus Anatomical Structure Development Tissue Development Toll-like Receptor 5 Signaling Pathway	RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Nucleus Organization Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Viral Genome Replication Regulation Of Myeloid Cell Differentiation Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing Immune Response Negative Regulation Of Viral Genome Replication Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Cellular Macromolecule Biosynthetic Process Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Viral Genome Replication Nuclear Speck Organization MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Cell Cycle Toll-like Receptor 4 Signaling Pathway Regulation Of MRNA Processing Regulation Of Metabolic Process Phosphorylation Intracellular Signal Transduction Intermembrane Transport Regulation Of RNA Splicing Cellular Response To Reactive Oxygen Species
Tagcloud ?		acetate ap1 avian began belong cooperative counterpart differentiate erbb erythroblastosis erythrocytic gata glycoproteins h5 homologues jb jbn jun mammal megakaryocytes megakaryocytic myristate oncogenes phorbol retroviruses thrombocytes thrombocytic transform transformed
Tagcloud (Difference) ?		acetate ap1 avian began belong cooperative counterpart differentiate erbb erythroblastosis erythrocytic gata glycoproteins h5 homologues jb jbn jun mammal megakaryocytes megakaryocytic myristate oncogenes phorbol retroviruses thrombocytes thrombocytic transform transformed
Tagcloud (Intersection) ?