FAM9B and BARD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM9B	BARD1
Gene Name		family with sequence similarity 9, member B	BRCA1 associated RING domain 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Ubiquitin Ligase Complex Nucleus Nucleoplasm Nucleolus Cytoplasm BRCA1-BARD1 Complex Intracellular Membrane-bounded Organelle BRCA1-A Complex
	Molecular Function		RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Kinase Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process		Tissue Homeostasis DNA Repair Cellular Response To DNA Damage Stimulus Cell Cycle Arrest Protein Ubiquitination Negative Regulation Of MRNA 3'-end Processing Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Protein Export From Nucleus Protein K6-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Androgen levels ( 22936694)	Neuroblastoma ( 22941191 21124317) Neuroblastoma (high-risk) ( 19412175)
Protein-Protein Interactions		118 interactors: ABT1 ACP6 ANKRD36B AP1M1 ASB6 ATF7 AURKAIP1 BAG6 BARD1 BCL2A1 BET1 BLOC1S2 BYSL C12orf10 C14orf105 C16orf72 C19orf57 C20orf195 C8orf33 CADPS CCDC106 CCDC116 CCDC70 CDC23 CDC42EP4 CDCA7L CENPL CEP57L1 CEP95 CHRAC1 CLCN1 CMTM6 COL20A1 CSDE1 CWF19L2 DAPK2 DAXX DENND2D DNAJC15 DNAJC4 EBNA1BP2 ECH1 EIF3G FAM161A FASTKD3 FCHSD2 FERD3L GFOD1 GOPC GPX1 GSTK1 ISCU LIN7A LNX1 LOC728175 LYRM2 MAB21L3 MFAP1 MOB1A MORF4L1 MORF4L2 MRPL10 MRPL28 MRPL9 MYO15B NDE1 NDUFB10 NEBL NOL4 PAGE1 PAGE3 PHYH PIN4 POLL PPP1R18 PRPF3 PSMD14 PTRH1 RAB17 RAD51B RBM17 RBM23 RMND1 RPL9 RSL24D1 RUSC1 SDCBP SDCBP2 SERPINE2 SFN SLC16A3 SLPI SMN2 SNAP29 SNAP47 SNX20 STK3 SUCLA2 SYT17 TBRG4 TCEA2 TCEANC TCEB3 TGFBI TRMT61B TSG101 TUFM TXN2 UBE2E2 URB1-AS1 XRCC4 YARS2 ZCCHC10 ZGPAT ZNF41 ZNF410 ZNF567 ZNF614	107 interactors: ACP1 AKIP1 AP1B1 ASH2L ATP1B1 ATP1B3 BCCIP BCL3 BRCA1 BRD7 BRIP1 CAP1 CASC1 CCDC136 CEP70 CHD3 CNTN4 COL1A1 COMMD1 CRIPAK CSTF1 DCC DDX39B EWSR1 EXOC5 FAM9B FEZ1 FKBP1A FKBP2 FKBP3 FUCA1 GIT1 GOLGA2 GPRASP2 H2AFX HAP1 HIST2H2AC HNRNPC HNRNPLL HSPA14 IDI1 IKBKAP ING5 KAT5 KAT7 KBTBD7 KRT40 LDOC1 LGALS3 LGALS8 LRIF1 MDC1 MRPS22 MSH2 MSH3 MSH6 MT2A ND1 NFKBIA NPC2 OLA1 PCBP2 PDXK PDZD8 PIAS1 PIAS4 POLR2A POLR2H POMZP3 POU2F1 PSMA7 PTN RBBP8 RBMY2BP RPS20 SELENBP1 SETDB1 SMCHD1 SNRNP200 SNX3 SPAG5 SRSF2 TCERG1 TMEM248 TOP1 TP53 TRAF1 TRAPPC11 TRAPPC8 TULP2 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBE2W UBE3A UBR5 UBXN1 WDR61 XRCC6 ZFP64 ZHX1 ZNF121
Entrez ID		171483	580
HPRD ID		15955	03354
Ensembl ID		ENSG00000177138	ENSG00000138376
Uniprot IDs		Q8IZU0 Q8N7Z8	Q99728
PDB IDs			1JM7 2NTE 2R1Z 3C5R 3FA2
Enriched GO Terms of Interacting Partners?		Mitochondrial Translation Organelle Organization Translational Elongation Vesicle Organization Gene Expression Mitochondrion Organization Synaptic Vesicle Priming Mitochondrial Translational Elongation Translation Establishment Of Vesicle Localization Vesicle Localization Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Cellular Component Assembly Cellular Metabolic Process Synaptic Vesicle Transport Mitochondrial Translational Initiation Mitochondrial Translational Termination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Cellular Macromolecular Complex Assembly Organelle Localization Translational Termination RNA Metabolic Process Translational Initiation Cellular Response To Stress Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Membrane Organization Protein Polyubiquitination Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Process Cellular Protein Complex Disassembly Intrinsic Apoptotic Signaling Pathway Ribosome Biogenesis Neurotransmitter Secretion Macromolecule Biosynthetic Process Vesicle Fusion Pigmentation Protein Complex Disassembly Synaptic Vesicle Exocytosis Viral Process Cellular Pigmentation	Cellular Response To DNA Damage Stimulus DNA Repair Protein Polyubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Nitrogen Compound Metabolic Process Double-strand Break Repair DNA Metabolic Process Gene Expression Chromosome Organization Regulation Of Metabolic Process Protein K48-linked Ubiquitination Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Protein Modification By Small Protein Conjugation RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Protein Ubiquitination Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Response To Stress Cell Cycle Checkpoint DNA Recombination Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Protein Ubiquitination Positive Regulation Of Cellular Metabolic Process Meiotic Mismatch Repair Cellular Macromolecule Biosynthetic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Modification-dependent Protein Catabolic Process Chromatin Organization DNA Damage Checkpoint Cellular Macromolecule Catabolic Process Immune System Process Viral Process Cell Cycle Proteolysis Involved In Cellular Protein Catabolic Process Organelle Organization Cellular Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated
Tagcloud ?			10ng agreed atr belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
Tagcloud (Difference) ?			10ng agreed atr belonged biosynthetic biphenyls brca2 dioxin fancd2 figf hands immunoblots impulses kcnma1 lactational mycn ndl neurobiological npy4r ontology operator6 pcbs performances projection rad51 scn1a summation transcriptomic validating
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