GADD45A and FBN3

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		GADD45A	FBN3
Gene Name		growth arrest and DNA-damage-inducible, alpha	fibrillin 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Proteinaceous Extracellular Matrix
	Molecular Function	Core Promoter Binding Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Activation Of MAPKKK Activity DNA Repair Negative Regulation Of Protein Kinase Activity Apoptotic Process Cell Cycle Arrest Centrosome Cycle Signal Transduction In Response To DNA Damage Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Cellular Response To Mechanical Stimulus Cellular Response To Ionizing Radiation Positive Regulation Of P38MAPK Cascade Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Molecules associated with elastic fibres Elastic fibre formation Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions		65 interactors: ADAP1 ASCC2 AURKA BAG6 C14orf1 CCNB1 CDK1 CDK11A CDKN1A CENPB CHD3 CLEC3B DCTN2 DNAJC13 EEF1A1 EEF1G FAM83D FAS FBN3 FTL GADD45GIP1 GAPDH GBP2 GNB2 HIST1H1A HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 IGHM IGSF21 JMJD1C KHSRP LMO4 MAP3K4 MAPK14 MASP1 MDM2 MICAL1 MIDN MPP1 NPM1 NRBP1 NUCB2 PCNA PFKFB4 PPARA PSMC3 PTN PTPRK QARS RAI1 RBPJ RPS2 RXRA SH3GLB1 SPTBN4 SYNE4 TLE1 TP53 UBE2D1 UBR1 VIM ZHX1 ZNF135	13 interactors: ANXA7 BID C11orf58 CDKN1A DAZAP2 GADD45A GSK3B NUDT21 PIK3R3 RPN2 RPS6KA6 TK1 TSC22D1
Entrez ID		1647	84467
HPRD ID		00528	10538
Ensembl ID		ENSG00000116717	ENSG00000142449
Uniprot IDs		A5JUZ3 P24522	Q75N90
PDB IDs		2KG4
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Cell Cycle Cell Cycle Process Regulation Of Gene Expression Mitotic Cell Cycle Mitotic Cell Cycle Process Cellular Response To Organic Substance Regulation Of Protein Metabolic Process Organelle Organization DNA Packaging DNA Conformation Change Negative Regulation Of Cellular Metabolic Process Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromosome Organization Cell Aging Protein Complex Assembly Chromatin Organization Negative Regulation Of Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Cell Death Death Positive Regulation Of Protein Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Catabolic Process Response To Organic Substance DNA Damage Checkpoint Chromatin Assembly Or Disassembly Stress-induced Premature Senescence Immune Response Mitotic Cell Cycle Checkpoint Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Mitotic DNA Damage Checkpoint Immune System Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cell Death Positive Regulation Of Metabolic Process Innate Immune Response Mitotic DNA Integrity Checkpoint Response To Toxic Substance Positive Regulation Of Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Proteolysis Cellular Response To Oxygen Levels	Signal Transduction In Response To DNA Damage Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Protein Kinase Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Mitochondrion Organization Cellular Response To Ionizing Radiation Negative Regulation Of Transferase Activity Regulation Of Apoptotic Process Negative Regulation Of Protein Phosphorylation Regulation Of Kinase Activity Cellular Response To Heat Regulation Of Phosphorus Metabolic Process Response To Metal Ion Fetal Process Involved In Parturition Cellular Response To Stress Regulation Of Cell Death Apoptotic Signaling Pathway Cellular Response To DNA Damage Stimulus Cellular Response To Mechanical Stimulus Response To Organic Substance Response To Organic Cyclic Compound DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Hormone Regulation Of Mitochondrion Organization Negative Regulation Of Type B Pancreatic Cell Development Skeletal Muscle Cell Proliferation Superior Temporal Gyrus Development Apoptotic Process Protein Oligomerization Regulation Of Intracellular Transport Programmed Cell Death Protein Tetramerization Extrinsic Apoptotic Signaling Pathway Response To External Stimulus Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Death Death Phosphorylation Intracellular Signal Transduction Response To Heat Signal Transduction By P53 Class Mediator Response To Inorganic Substance Re-entry Into Mitotic Cell Cycle
Tagcloud ?		2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Difference) ?		2h5 accompanies anova dynactin gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 rad23a raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase
Tagcloud (Intersection) ?