U2AF2 and SAP30BP

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		U2AF2	SAP30BP
Gene Name		U2 small nuclear RNA auxiliary factor 2	SAP30 binding protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Prp19 Complex Nucleoplasm Spliceosomal Complex Nuclear Speck	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Nucleotide Binding Protein Binding Enzyme Binding Poly(A) RNA Binding C2H2 Zinc Finger Domain Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Gene Expression Positive Regulation Of Cell Death Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	NoRC negatively regulates rRNA expression Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		51 interactors: AES APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX17 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA HNRNPA0 HNRNPD HNRNPK IL7R KHDRBS1 KHDRBS3 KIAA0907 LURAP1 MAP1B PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TOP1 U2AF1 WT1 ZRSR2	23 interactors: CSNK2A1 DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 WDR77 WDR83 ZNF212 ZNF408
Entrez ID		11338	29115
HPRD ID		01872	17094
Ensembl ID		ENSG00000063244	ENSG00000161526
Uniprot IDs		P26368	F5H478 Q9UHR5
PDB IDs		1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Biosynthetic Process Spliceosomal Complex Assembly Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Metabolic Process Regulation Of MRNA Processing Termination Of RNA Polymerase II Transcription Regulation Of MRNA Stability Regulation Of RNA Stability Cellular Process DNA-templated Transcription, Termination Regulation Of Translation MRNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Female Gonad Development Circadian Regulation Of Translation RNA 3'-end Processing	MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Export Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Thrombin Receptor Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of Biosynthetic Process Muscle Structure Development Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Protein Binding Regulation Of Neuronal Synaptic Plasticity Cellular Process Apoptotic Process MRNA Export From Nucleus
Tagcloud ?		acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine
Tagcloud (Difference) ?		acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine
Tagcloud (Intersection) ?