LYST and DNAJC14

Number of citations of the paper that reports this interaction (PMID 11984006)
18

Data Source:
HPRD (in vitro)

		LYST	DNAJC14
Gene Name		lysosomal trafficking regulator	DnaJ (Hsp40) homolog, subfamily C, member 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Endomembrane System Microtubule Cytoskeleton Extrinsic Component Of Membrane	Nucleoplasm Nucleolus Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Phospholipid Binding
	Biological Process	Neutrophil Mediated Immunity T Cell Mediated Immunity Phospholipid Metabolic Process Microtubule-based Process Lysosome Organization Blood Coagulation Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Response To Drug Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Phospholipid Homeostasis	Protein Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DGCR14 DNAJC14 EFS ESRRA HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521	3 interactors: AGTR1 DRD1 LYST
Entrez ID		1130	85406
HPRD ID		06060	12082
Ensembl ID		ENSG00000143669	ENSG00000135392
Uniprot IDs		Q99698	Q6Y2X3
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Mitochondrion Organization Protein Targeting Alternative MRNA Splicing, Via Spliceosome Regulation Of Mitochondrion Organization Centriole Replication Membrane Organization Gene Expression Protein Transport Centriole Assembly Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Centrosome Duplication ERBB Signaling Pathway Positive Regulation Of Transport Substantia Nigra Development Regulation Of Intracellular Transport Intrinsic Apoptotic Signaling Pathway Nervous System Development Positive Regulation Of Apoptotic Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neural Nucleus Development Intracellular Protein Transport Centrosome Cycle Protein Localization Positive Regulation Of Intracellular Transport Apoptotic Process Establishment Of Localization In Cell Developmental Process Mitochondrial Translational Elongation Mitochondrial Translational Initiation Mitochondrial Translational Termination Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Programmed Cell Death Intracellular Transport Regulation Of Cellular Localization Cell Death Death Anatomical Structure Development Mitochondrial Translation System Development Midbrain Development Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity RNA Splicing	Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Ion Homeostasis Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Blood Vessel Size Regulation Of Tube Size Cell Migration Chemical Homeostasis Cell Motility Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Cell Chemotaxis Locomotion Cytosolic Calcium Ion Homeostasis Homeostatic Process Sensitization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Movement Of Cell Or Subcellular Component Positive Regulation Of NAD(P)H Oxidase Activity Habituation Cellular Calcium Ion Homeostasis Renin-angiotensin Regulation Of Aldosterone Production Response To External Stimulus Calcium Ion Homeostasis Blood Circulation Nonassociative Learning Positive Regulation Of Phospholipase A2 Activity Regulation Of Blood Vessel Size By Renin-angiotensin Endosome Transport Via Multivesicular Body Sorting Pathway Operant Conditioning Regulation Of NAD(P)H Oxidase Activity Angiotensin-activated Signaling Pathway Conditioned Taste Aversion Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Cellular Metal Ion Homeostasis Secretion Of Lysosomal Enzymes Cerebral Cortex GABAergic Interneuron Migration Phospholipase C-activating Dopamine Receptor Signaling Pathway Glucose Import Cellular Cation Homeostasis Cellular Ion Homeostasis Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Cholesterol Esterification Interneuron Migration From The Subpallium To The Cortex Phospholipid Homeostasis Metal Ion Homeostasis Regulation Of Cholesterol Esterification Dopamine Transport
Tagcloud ?		ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?		ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?