LYST and NCDN

Number of citations of the paper that reports this interaction (PMID 11984006)
18

Data Source:
HPRD (in vivo, two hybrid)

		LYST	NCDN
Gene Name		lysosomal trafficking regulator	neurochondrin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Endomembrane System Microtubule Cytoskeleton Extrinsic Component Of Membrane	Nucleus Cytosol Membrane Axon Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding Phospholipid Binding
	Biological Process	Neutrophil Mediated Immunity T Cell Mediated Immunity Phospholipid Metabolic Process Microtubule-based Process Lysosome Organization Blood Coagulation Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Response To Drug Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Phospholipid Homeostasis	Neuron Projection Development Bone Resorption Regulation Of Neuronal Synaptic Plasticity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DGCR14 DNAJC14 EFS ESRRA HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521	8 interactors: A2M ACD AES EFHC2 LYST POT1 SEMA4C TINF2
Entrez ID		1130	23154
HPRD ID		06060	10530
Ensembl ID		ENSG00000143669	ENSG00000020129
Uniprot IDs		Q99698	Q9UBB6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Mitochondrion Organization Protein Targeting Alternative MRNA Splicing, Via Spliceosome Regulation Of Mitochondrion Organization Centriole Replication Membrane Organization Gene Expression Protein Transport Centriole Assembly Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Centrosome Duplication ERBB Signaling Pathway Positive Regulation Of Transport Substantia Nigra Development Regulation Of Intracellular Transport Intrinsic Apoptotic Signaling Pathway Nervous System Development Positive Regulation Of Apoptotic Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neural Nucleus Development Intracellular Protein Transport Centrosome Cycle Protein Localization Positive Regulation Of Intracellular Transport Apoptotic Process Establishment Of Localization In Cell Developmental Process Mitochondrial Translational Elongation Mitochondrial Translational Initiation Mitochondrial Translational Termination Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Programmed Cell Death Intracellular Transport Regulation Of Cellular Localization Cell Death Death Anatomical Structure Development Mitochondrial Translation System Development Midbrain Development Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity RNA Splicing	Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Negative Regulation Of DNA Replication Telomere Maintenance Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of DNA Replication Regulation Of Telomerase Activity Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Replication Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of Biosynthetic Process Homeostatic Process Regulation Of Protein ADP-ribosylation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Complement Activation, Lectin Pathway Mast Cell Secretory Granule Organization Telomere Formation Via Telomerase Negative Regulation Of Protein Glycosylation Positive Regulation Of Anoikis Protection From Non-homologous End Joining At Telomere Endosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Helicase Activity Regulation Of Organelle Organization Positive Regulation Of Telomere Maintenance Via Telomerase Secretion Of Lysosomal Enzymes Chromosome Organization Regulation Of Binding DNA Metabolic Process Phospholipid Homeostasis Cellular Localization Regulation Of Protein Glycosylation Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor	af affymetrix aforementioned altogether anulus back basp1 believed brachyury cd155 cd221 cd24 cd90 characterizing degeneration disc exception fibrosus identifies ihc immature intervertebral ivd np nrp possessed pulposus regenerative select
Tagcloud (Difference) ?		ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor	af affymetrix aforementioned altogether anulus back basp1 believed brachyury cd155 cd221 cd24 cd90 characterizing degeneration disc exception fibrosus identifies ihc immature intervertebral ivd np nrp possessed pulposus regenerative select
Tagcloud (Intersection) ?