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COPS6 and C4orf17
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
COPS6
C4orf17
Gene Name
COP9 signalosome subunit 6
chromosome 4 open reading frame 17
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
COP9 Signalosome
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Cullin Deneddylation
Viral Process
Pathways
Drugs
Diseases
GWAS
Eating disorders (
23568457
)
Metabolite levels (MHPG) (
23319000
)
Protein-Protein Interactions
84 interactors:
ANXA1
ANXA7
BTBD2
C1orf174
C4orf17
CASP3
CASP6
CASP7
CASP8
CCDC106
CDH10
CDKN1A
CDKN2C
CHRNB1
COPS2
COPS3
COPS4
COPS5
COPS8
COX17
COX5A
CRELD1
CUL1
CUL5
DIS3L2
DLEU1
EDN1
EIF3E
EMD
EP300
ERH
FAU
GPS1
HMOX2
JUN
LAMA4
LPL
MAP7D1
MAPK6
MAPKAPK3
MIF
MNAT1
MYCBP
NEDD8
NR3C1
ORAI2
PAEP
PAFAH1B3
PBX2
PDZK1IP1
PFKL
PHYHIP
PMF1
PRKRA
PSAP
PSMD11
PTEN
QTRT1
RAB27A
RBX1
RFC5
ROGDI
RPA2
RPL15
S100A10
SAT1
SERPINA5
SERPINB9
SLC2A1
SMN1
SNRPG
STK40
STX5
SULT1E1
TDGF1
TK1
TP53
TP63
TRDMT1
TRIB3
VIM
WIPI2
ZEB2
ZNF24
7 interactors:
CHD3
COPS6
KDM1A
PRMT1
SH3GL3
SUV39H1
TUBA4A
Entrez ID
10980
84103
HPRD ID
16735
12825
Ensembl ID
ENSG00000168090
ENSG00000138813
Uniprot IDs
Q7L5N1
Q53FE4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cullin Deneddylation
Protein Deneddylation
Developmental Process
Intrinsic Apoptotic Signaling Pathway
Cellular Metabolic Process
Anatomical Structure Development
Regulation Of Protein Metabolic Process
Regulation Of Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Regulation Of Catalytic Activity
Tissue Development
Mitotic Cell Cycle
Programmed Cell Death
Apoptotic Signaling Pathway
Response To Stress
Cell Death
Catabolic Process
Death
Regulation Of Cell Proliferation
Mitotic Cell Cycle Process
Cellular Response To Stress
Response To Abiotic Stimulus
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Apoptotic Process
Regulation Of Phosphorylation
Response To Organic Cyclic Compound
Cell Cycle
Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cellular Metabolic Process
Cell Cycle Phase Transition
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Cycle
Organ Development
Multicellular Organismal Development
Epithelium Development
Positive Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Cell Death
Response To Stimulus
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Programmed Cell Death
System Development
Negative Regulation Of Cell Death
Cellular Macromolecule Catabolic Process
Response To Organic Substance
Regulation Of Protein Kinase Activity
Positive Regulation Of Cell Death
Regulation Of Megakaryocyte Differentiation
Chromatin Modification
Chromatin Organization
Regulation Of Hematopoietic Progenitor Cell Differentiation
Chromosome Organization
Histone Modification
Regulation Of Primitive Erythrocyte Differentiation
Histone Methylation
Organelle Organization
Protein Methylation
Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Megakaryocyte Differentiation
Histone H3-K9 Dimethylation
Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Negative Regulation Of Histone H3-K4 Methylation
Histone H3-K9 Demethylation
Histone H3-K4 Demethylation
Cullin Deneddylation
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Positive Regulation Of Megakaryocyte Differentiation
Cellular Protein Metabolic Process
Histone H3-K9 Trimethylation
Protein Deneddylation
Peptidyl-lysine Dimethylation
Positive Regulation Of Hormone Biosynthetic Process
Peptidyl-arginine N-methylation
Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Negative Regulation Of Histone H3-K9 Methylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Histone H4-R3 Methylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Chromatin Silencing At RDNA
Granulocyte Differentiation
Histone Arginine Methylation
Cell Cycle
Peptidyl-arginine Methylation
Negative Regulation Of Histone Methylation
Methylation
Positive Regulation Of Erythrocyte Differentiation
Negative Regulation Of Circadian Rhythm
Blood Coagulation
Hemostasis
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Histone H3-K9 Methylation
Microtubule Cytoskeleton Organization
Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Hormone Biosynthetic Process
Tagcloud
?
aiming
aip
alignment
boar
brms1
chordc1
clues
csde1
csfv
ddx5
domestic
fever
gnb2l1
hemorrhagic
hspa8
interactive
metap2
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h
Tagcloud (Difference)
?
aiming
aip
alignment
boar
brms1
chordc1
clues
csde1
csfv
ddx5
domestic
fever
gnb2l1
hemorrhagic
hspa8
interactive
metap2
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h
Tagcloud (Intersection)
?