APPBP2 and PPP1R8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		APPBP2	PPP1R8
Gene Name		amyloid beta precursor protein (cytoplasmic tail) binding protein 2	protein phosphatase 1, regulatory subunit 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck
	Molecular Function	Microtubule Motor Activity Protein Binding	DNA Binding RNA Binding Endonuclease Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Type 1 Regulator Activity Ribonuclease E Activity
	Biological Process	Intracellular Protein Transport Metabolic Process Intracellular Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing RNA Catabolic Process Cell Proliferation RNA Splicing Negative Regulation Of Catalytic Activity RNA Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747	24 interactors: APP APPBP2 C14orf1 CDC5L CRMP1 CSNK2A1 CSNK2A2 CTNNBL1 EED FBXO25 GBP2 HDAC2 HMGA1 LYN MELK PPIL1 PPP1CA PPP1CC PRKACA RBM48 SETDB1 SF3B1 STC2 WDR77
Entrez ID		10513	5511
HPRD ID		05616	04028
Ensembl ID		ENSG00000062725	ENSG00000117751
Uniprot IDs		Q92624	Q12972 Q6ICT4
PDB IDs			3V4Y
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance	Response To External Stimulus Triglyceride Catabolic Process Cellular Protein Modification Process Acylglycerol Catabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression MRNA Metabolic Process RNA Metabolic Process RNA Processing RNA Splicing Chemotaxis Developmental Process Multicellular Organismal Development System Development Axon Guidance Cellular Protein Metabolic Process Chromatin Organization Response To Abiotic Stimulus Circadian Regulation Of Gene Expression Metabolic Process Regulation Of Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Process Neuron Projection Development Cellular Metabolic Process Triglyceride Metabolic Process Regulation Of Platelet Aggregation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Axonogenesis Anatomical Structure Development Neutral Lipid Metabolic Process Axon Development Rhythmic Process Regulation Of Cell Cycle Cell Cycle Cellular Nitrogen Compound Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Chromatin Modification Neuron Development Entrainment Of Circadian Clock By Photoperiod Apoptotic Process Response To Light Stimulus Photoperiodism Entrainment Of Circadian Clock Programmed Cell Death Chromosome Organization
Tagcloud ?		10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?