APPBP2 and CSNK1G2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		APPBP2	CSNK1G2
Gene Name		amyloid beta precursor protein (cytoplasmic tail) binding protein 2	casein kinase 1, gamma 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane	Nucleus Cytosol Membrane
	Molecular Function	Microtubule Motor Activity Protein Binding	Magnesium Ion Binding Glycoprotein Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Peptide Binding Phosphoprotein Binding
	Biological Process	Intracellular Protein Transport Metabolic Process Intracellular Transport	Protein Phosphorylation Sphingolipid Metabolic Process Endocytosis Signal Transduction Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Protein Autophosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			disassembly of the destruction complex and recruitment of AXIN to the membrane Sphingolipid metabolism Metabolism of lipids and lipoproteins misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT Sphingolipid de novo biosynthesis RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747	13 interactors: APP APPBP2 C2orf44 COL4A3BP DBNDD2 KRTAP10-7 MTA1 NCK1 PER1 PPP1R14A RAP1GAP RUNDC3B SMAD3
Entrez ID		10513	1455
HPRD ID		05616	03738
Ensembl ID		ENSG00000062725	ENSG00000133275
Uniprot IDs		Q92624	P78368
PDB IDs			2C47
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance	Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Negative Regulation Of Phosphorylation Posttranscriptional Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Translation Regulation Of Inflammatory Response Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Protein Metabolic Process Response To Light Stimulus Positive Regulation Of Transforming Growth Factor Beta3 Production Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Cap-independent Translational Initiation Negative Regulation Of Microvillus Assembly Negative Regulation Of Protein Metabolic Process Circadian Regulation Of Gene Expression Response To External Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Circadian Rhythm Positive Regulation Of Translation In Response To Stress Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Synaptic Growth At Neuromuscular Junction ER To Golgi Ceramide Transport Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Protein Autoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Response To Radiation Regulation Of Protein Phosphorylation Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Peptidyl-serine Dephosphorylation Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Protein Autoubiquitination Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Positive Regulation Of Protein Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Ceramide Transport Positive Regulation Of Peptidase Activity Positive Regulation Of Metabolic Process
Tagcloud ?		10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?