IKZF1 and CSNK1G1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		IKZF1	CSNK1G1
Gene Name		IKAROS family zinc finger 1 (Ikaros)	casein kinase 1, gamma 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex	Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye	Endocytosis Regulation Of Cell Shape Wnt Signaling Pathway Peptidyl-serine Phosphorylation
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581	11 interactors: APP C2orf44 CEP76 FAM219A FOXO1 IKZF1 KRTAP10-7 MKRN1 PPP1R14A RELA RUNDC3B
Entrez ID		10320	53944
HPRD ID		04318	05886
Ensembl ID		ENSG00000185811	ENSG00000169118
Uniprot IDs		Q13422	Q9HCP0 U3KQB3
PDB IDs			2CMW
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Oxidative Stress Positive Regulation Of Neutrophil Differentiation Acetaldehyde Metabolic Process Regulation Of Multicellular Organism Growth Cellular Response To Reactive Oxygen Species Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Positive Regulation Of Schwann Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Schwann Cell Differentiation Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Response To Cobalamin Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Reactive Oxygen Species Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MiRNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Receptor Signaling Pathway Innate Immune Response Cellular Response To Oxidative Stress Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Cold Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Positive Regulation Of NK T Cell Differentiation Axon Choice Point Recognition Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Nicotine Positive Regulation Of Granulocyte Differentiation Neuron Remodeling Cellular Response To Hyperoxia Negative Regulation Of Cellular Metabolic Process Fc Receptor Signaling Pathway Immune System Process Regulation Of MiRNA Metabolic Process Response To Insulin Regulation Of Energy Homeostasis Regulation Of Centriole Replication Regulation Of Developmental Growth Response To Abiotic Stimulus Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?