IKZF1 and SYT17

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF1	SYT17
Gene Name		IKAROS family zinc finger 1 (Ikaros)	synaptotagmin XVII
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex	Trans-Golgi Network Synaptic Vesicle Membrane
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Transporter Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye	Exocytosis
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)	Alcohol dependence ( 21876473)
Protein-Protein Interactions		75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581	18 interactors: APP APTX CCDC85B CEP63 CEP70 CHMP4A FAM9B GMCL1 IKZF1 MEOX1 MEOX2 MID2 NIF3L1 NINL RUNDC3A SSX2IP TRAF2 TSC22D4
Entrez ID		10320	51760
HPRD ID		04318	17425
Ensembl ID		ENSG00000185811
Uniprot IDs		Q13422	H3BN78 H3BRH9 Q9BSW7
PDB IDs			2ENP
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing	Somite Specification Segment Specification G2/M Transition Of Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Neuron Death Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Polynucleotide 3' Dephosphorylation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Mitotic Cell Cycle Somitogenesis Positive Regulation Of Transcription, DNA-templated Embryonic Pattern Specification Cell Cycle Centrosome Organization Negative Regulation Of Autophagic Vacuole Assembly Dihydrobiopterin Metabolic Process Collateral Sprouting In Absence Of Injury Somite Development Regulation Of Multicellular Organism Growth Negative Regulation Of Cellular Metabolic Process Microtubule Organizing Center Organization Sclerotome Development Response To Oxidative Stress Positive Regulation Of Macromolecule Biosynthetic Process Segmentation Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Microtubule-based Transport Intraciliary Transport Involved In Cilium Morphogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cytoskeleton-dependent Intracellular Transport Positive Regulation Of NK T Cell Differentiation Viral Budding Via Host ESCRT Complex Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Protein Binding
Tagcloud ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?		agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?