BET1 and STX4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BET1	STX4
Gene Name		Bet1 golgi vesicular membrane trafficking protein	syntaxin 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cis-Golgi Network Membrane Integral Component Of Membrane Golgi Cisterna	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Syntaxin Binding	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Protein Transport Vesicle Fusion With Golgi Apparatus	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways			Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Aging ( 22773346) Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: BCL2L13 CCDC155 FAM9B MAGEA6 STX4 STX5 USHBP1	48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B
Entrez ID		10282	6810
HPRD ID		16107	01722
Ensembl ID		ENSG00000105829	ENSG00000103496
Uniprot IDs		O15155 Q53XK0 Q68DU7	A8MXY0 B7Z425 Q12846
PDB IDs		3EGX
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Organelle Fusion Vesicle Docking Membrane Docking Chromosome Localization To Nuclear Envelope Involved In Synapsis Membrane Fusion Positive Regulation Of Eosinophil Degranulation Golgi Disassembly Vesicle Organization Golgi Vesicle Transport Golgi Inheritance Positive Regulation Of Protein Localization To Cell Surface Regulation Of Golgi Organization Vesicle Fusion With Golgi Apparatus Positive Regulation Of Immunoglobulin Secretion Establishment Of Organelle Localization SNARE Complex Assembly Early Endosome To Golgi Transport Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Regulation Of Immunoglobulin Secretion Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Response To Hydroperoxide Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Establishment Of Localization In Cell Positive Regulation Of Protein Localization To Plasma Membrane Organelle Disassembly Positive Regulation Of Immunoglobulin Production Regulation Of Regulated Secretory Pathway Establishment Of Chromosome Localization Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Localization	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis
Tagcloud ?		attachment clusters compartment crosstalk diminished endoplasmic er ethylmaleimide golgi intermediate knockdown manipulation morphology neurodegenerative novo pathophysiologic phenomena precedes processing reticulum reversed secretion snare stress stressors syntaxin syx5 tubular vesicular	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Difference) ?		attachment clusters compartment crosstalk diminished endoplasmic er ethylmaleimide golgi intermediate knockdown manipulation morphology neurodegenerative novo pathophysiologic phenomena precedes processing reticulum reversed secretion snare stress stressors syntaxin syx5 tubular vesicular	address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a
Tagcloud (Intersection) ?