STX4 and CYBRD1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STX4	CYBRD1
Gene Name		syntaxin 4	cytochrome b reductase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Intracellular Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane Brush Border Membrane Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity	Ferric-chelate Reductase Activity Oxidoreductase Activity, Oxidizing Metal Ions Metal Ion Binding
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Blood Coagulation Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Platelet Activation Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Membrane Response To Hydroperoxide SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Membrane Organization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface	Cellular Iron Ion Homeostasis Response To Iron Ion Transmembrane Transport Oxidation-reduction Process
Pathways		Response to elevated platelet cytosolic Ca2+ Translocation of GLUT4 to the plasma membrane Disinhibition of SNARE formation Platelet activation, signaling and aggregation trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Iron uptake and transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		48 interactors: ACTB BET1 CYBRD1 DLG1 GIMAP5 GOSR2 ITSN2 LLGL1 NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPT5 SNAP23 SNAP25 SNAP29 SNAP47 STX12 STX16 STX3 STX5 STX6 STX7 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VAPB VTI1B	2 interactors: NEDD4L STX4
Entrez ID		6810	79901
HPRD ID		01722	05764
Ensembl ID		ENSG00000103496	ENSG00000071967
Uniprot IDs		A8MXY0 B7Z425 Q12846	Q53TN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Organization Vesicle Organization Establishment Of Localization In Cell Cellular Localization Exocytosis Secretion By Cell Secretion Transport Golgi Vesicle Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Neurotransmitter Secretion Regulation Of Exocytosis Regulation Of Cellular Localization Vesicle Docking Regulation Of Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Docking Regulation Of Neurotransmitter Levels Intracellular Protein Transport Neurotransmitter Transport Synaptic Vesicle Exocytosis Vesicle Fusion With Golgi Apparatus Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Secretion Establishment Of Vesicle Localization Vesicle Localization Cell-cell Signaling Organelle Organization Endomembrane System Organization Cytoplasmic Transport SNARE Complex Assembly Endosomal Transport Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Organelle Localization Establishment Of Organelle Localization Synaptic Transmission Golgi To Plasma Membrane Transport Regulation Of Protein Localization ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Exocytosis	Regulation Of Protein Localization To Cell Surface Positive Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Eosinophil Degranulation Regulation Of Vesicle-mediated Transport Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Protein Localization To Cell Surface Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Immunoglobulin Secretion Regulation Of Tight Junction Assembly SNARE Complex Assembly Regulation Of Cellular Component Movement Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Sodium Ion Transport Positive Regulation Of Transport Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Regulation Of Protein Localization Regulation Of Immunoglobulin Secretion Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Regulated Secretory Pathway Negative Regulation Of Potassium Ion Transport Negative Regulation Of Systemic Arterial Blood Pressure Regulation Of Membrane Repolarization Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Response To Hydroperoxide Sodium Ion Homeostasis Regulation Of Cellular Localization Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Protein Localization To Plasma Membrane Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Cation Channel Activity Positive Regulation Of Sodium Ion Transport Cardiac Muscle Cell Action Potential Regulation Of Membrane Depolarization Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Receptor-mediated Endocytosis Response To Salt Stress Regulation Of Potassium Ion Transmembrane Transport Protein K48-linked Ubiquitination Positive Regulation Of Immunoglobulin Production Negative Regulation Of Transporter Activity Regulation Of Regulated Secretory Pathway Protein Monoubiquitination Regulation Of Establishment Of Protein Localization To Plasma Membrane
Tagcloud ?		address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a	advanced altered angiogenic angpt apoptic cd34 clone controls cycle damaged expansion genes hbg1 hbg2 hspa1b immune included loss lymphopoiesis malignant mds myc oncogenes play profiles proto regulated repair together
Tagcloud (Difference) ?		address ageing armx3 b2mg consequence dep1 ebp50 effectors fact issue lancl1 maintaining modulators note ntal organismal pld3 preferentially recognize screened senescence senescent sorting straightforward triggering utilized vamp3 view vps26a	advanced altered angiogenic angpt apoptic cd34 clone controls cycle damaged expansion genes hbg1 hbg2 hspa1b immune included loss lymphopoiesis malignant mds myc oncogenes play profiles proto regulated repair together
Tagcloud (Intersection) ?