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CALCOCO2 and MID2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CALCOCO2
MID2
Gene Name
calcium binding and coiled-coil domain 2
midline 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Golgi Apparatus
Cytoskeleton
Membrane
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Cytoplasm
Microtubule
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Protein Homodimerization Activity
Microtubule Binding
Zinc Ion Binding
Ligase Activity
Protein Homodimerization Activity
Protein Heterodimerization Activity
Phosphoprotein Binding
Biological Process
Viral Process
Response To Interferon-gamma
Protein Ubiquitination
Negative Regulation Of Viral Transcription
Protein Localization To Microtubule
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Viral Release From Host Cell
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
143 interactors:
ABLIM1
ADSL
AES
AKAP17A
AMMECR1
AP5B1
APEX2
ARHGEF39
ARHGEF5
ARNT2
BAHD1
BCL6B
BEX2
C20orf195
CBX8
CCDC185
CCDC33
CCNH
CEP57L1
CHCHD3
CPNE7
CWF19L2
DAXX
DAZAP2
DBNDD2
DCTN4
DCX
DDIT4L
DDX6
DOCK2
DUSP12
DUSP26
EEF1E1
ENKD1
EXOSC5
FAM107A
FAM161A
FAM168A
FAM189A2
FAM90A1
FARS2
FASTK
FBF1
FBXL18
FKBPL
FXR2
GABARAPL1
GABARAPL2
GATAD2B
GEMIN4
GIT2
GLYCTK
HDAC7
HOXB9
IKBKG
KANSL1
KAT7
KLHL42
LENG1
LGALS8
LIMS2
LITAF
LMF2
LMO2
LMO4
LNX1
LONRF1
LSM4
MAGOHB
MAVS
MCM10
METTL17
MID2
MOS
MTPAP
MVP
MXI1
MYO6
NAA10
NDN
NFU1
ORC5
PAPD4
PCGF1
PEF1
PEG10
PFDN5
PHF1
PIAS4
POLI
PPP1R18
PRKAB2
PRPF31
PSMA1
PSME4
PTBP1
PTBP2
RABL6
RB1CC1
RBM15
RHPN1
RIN1
RNF11
RPA2
RPL9
RPS27A
RTN4IP1
RTP5
SDCBP
SHC1
SLC15A3
SMARCD1
SMCP
SNRPB
SPATA24
SRI
STK16
TAX1BP1
TBC1D22B
TBK1
TBRG4
TCEB3B
TCL1A
TEKT3
TP53RK
TRAF2
TRAF4
TRAF6
UBAC2
UBB
UBC
VARS
VPS72
ZC2HC1C
ZNF101
ZNF205
ZNF337
ZNF408
ZNF426
ZNF451
ZNF564
ZNF581
ZNF638
108 interactors:
ADAMTSL4
AEN
AQP1
ATRIP
BCL6B
BRCA1
BRMS1L
BYSL
C19orf66
CALCOCO2
CBX8
CCDC120
CCDC42
CCHCR1
CEP57L1
CHD2
CTSZ
DCX
DGCR6
DGCR6L
DIEXF
DMRT3
DYDC1
FAM107A
FAM161A
FAM214A
FAM90A1
FARS2
FBF1
FBXL18
FRMD6
GFI1B
GMCL1
GOLGA2
GORASP2
HOXB9
IGBP1
ISCU
JOSD1
KIAA1683
KIF1A
KIFC3
LENG1
LGALS14
LGALS8
MAGOHB
METTL17
MFAP1
MID1
MID1IP1
MOS
MVP
NR1D2
NXF1
OTUB2
PPP1R18
PRPF31
PSMA1
PTCD2
RCOR3
RPH3AL
RPP25L
RUNX1T1
SCNM1
SDCBP
SLC25A48
SLC25A6
SNAI1
SNAP47
SPATA24
SPG21
SPRY2
STX11
SYT17
TCEA2
TCEB3
THAP7
TOP3B
TRIM27
TRIM29
TRIM32
TRIM42
TRIM54
TRPV6
TSGA10
UBE2D1
UBE2D4
UBE2E2
UBE2E3
UBE2U
UBTD1
UNC45A
UTP23
WT1-AS
ZBTB24
ZC2HC1C
ZFYVE21
ZGPAT
ZNF165
ZNF24
ZNF250
ZNF417
ZNF440
ZNF564
ZNF587
ZNF785
ZNF792
ZSCAN12
Entrez ID
10241
11043
HPRD ID
06846
02191
Ensembl ID
ENSG00000136436
Uniprot IDs
Q13137
Q9UJV3
PDB IDs
3VVV
3VVW
4GXL
4HAN
2DJA
2DMK
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Type I Interferon Production
MRNA Metabolic Process
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
JNK Cascade
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Protein Modification By Small Protein Conjugation
Activation Of MAPK Activity
Activation Of Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Positive Regulation Of Protein Modification Process
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Type I Interferon Production
Activation Of NF-kappaB-inducing Kinase Activity
Protein Ubiquitination
Toll-like Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Mitotic G1 DNA Damage Checkpoint
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Protein Polyubiquitination
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Protein K63-linked Ubiquitination
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Protein K48-linked Ubiquitination
Negative Regulation Of Nucleic Acid-templated Transcription
Biosynthetic Process
Cellular Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Negative Regulation Of Cellular Metabolic Process
Protein K11-linked Ubiquitination
Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Maturation Of SSU-rRNA
Cellular Metabolic Process
Negative Regulation Of Microtubule Depolymerization
Protein K6-linked Ubiquitination
Regulation Of Microtubule-based Process
Ribosomal Small Subunit Biogenesis
Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Microtubule Polymerization Or Depolymerization
Synaptic Vesicle Fusion To Presynaptic Membrane
Negative Regulation Of Transferase Activity
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Viral Transcription
Regulation Of Histone H3-K4 Methylation
Regulation Of Microtubule Polymerization Or Depolymerization
Tagcloud
?
ad
astrocytes
atg
atgs
autophagic
autophagy
avs
beneficial
brains
clear
clearance
enhancement
expected
facilitating
flux
hippocampal
impairment
lc3
localized
microglia
mouse
ndp52
p62
phosphorylated
plaques
reflecting
sqstm1
tau
vesicles
Tagcloud (Difference)
?
ad
astrocytes
atg
atgs
autophagic
autophagy
avs
beneficial
brains
clear
clearance
enhancement
expected
facilitating
flux
hippocampal
impairment
lc3
localized
microglia
mouse
ndp52
p62
phosphorylated
plaques
reflecting
sqstm1
tau
vesicles
Tagcloud (Intersection)
?