MID2 and TOP3B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MID2	TOP3B
Gene Name		midline 2	topoisomerase (DNA) III beta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Extracellular Vesicular Exosome	Condensed Chromosome Nucleus Nucleoplasm
	Molecular Function	Microtubule Binding Zinc Ion Binding Ligase Activity Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding	DNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I Activity Poly(A) RNA Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Viral Transcription Protein Localization To Microtubule Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell	DNA Topological Change Chromosome Segregation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		108 interactors: ADAMTSL4 AEN AQP1 ATRIP BCL6B BRCA1 BRMS1L BYSL C19orf66 CALCOCO2 CBX8 CCDC120 CCDC42 CCHCR1 CEP57L1 CHD2 CTSZ DCX DGCR6 DGCR6L DIEXF DMRT3 DYDC1 FAM107A FAM161A FAM214A FAM90A1 FARS2 FBF1 FBXL18 FRMD6 GFI1B GMCL1 GOLGA2 GORASP2 HOXB9 IGBP1 ISCU JOSD1 KIAA1683 KIF1A KIFC3 LENG1 LGALS14 LGALS8 MAGOHB METTL17 MFAP1 MID1 MID1IP1 MOS MVP NR1D2 NXF1 OTUB2 PPP1R18 PRPF31 PSMA1 PTCD2 RCOR3 RPH3AL RPP25L RUNX1T1 SCNM1 SDCBP SLC25A48 SLC25A6 SNAI1 SNAP47 SPATA24 SPG21 SPRY2 STX11 SYT17 TCEA2 TCEB3 THAP7 TOP3B TRIM27 TRIM29 TRIM32 TRIM42 TRIM54 TRPV6 TSGA10 UBE2D1 UBE2D4 UBE2E2 UBE2E3 UBE2U UBTD1 UNC45A UTP23 WT1-AS ZBTB24 ZC2HC1C ZFYVE21 ZGPAT ZNF165 ZNF24 ZNF250 ZNF417 ZNF440 ZNF564 ZNF587 ZNF785 ZNF792 ZSCAN12	18 interactors: ADAMTSL4 C1QBP CENPF CHD8 CHIC2 FBLN5 GRN KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF408
Entrez ID		11043	8940
HPRD ID		02191	04662
Ensembl ID			ENSG00000100038
Uniprot IDs		Q9UJV3	A8K4N2 O95985
PDB IDs		2DJA 2DMK
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Protein Polyubiquitination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Protein K63-linked Ubiquitination Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Protein K48-linked Ubiquitination Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Cellular Process Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Protein K11-linked Ubiquitination Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Cellular Metabolic Process Negative Regulation Of Microtubule Depolymerization Protein K6-linked Ubiquitination Regulation Of Microtubule-based Process Ribosomal Small Subunit Biogenesis Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Microtubule Polymerization Or Depolymerization Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Transferase Activity Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Regulation Of Viral Transcription Regulation Of Histone H3-K4 Methylation Regulation Of Microtubule Polymerization Or Depolymerization	Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Interleukin-4 Biosynthetic Process Negative Regulation Of Mast Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription DNA Duplex Unwinding DNA Geometric Change Positive Regulation Of Trophoblast Cell Migration Negative Regulation Of MDA-5 Signaling Pathway Mitral Valve Formation Cellular Macromolecule Biosynthetic Process Regulation Of Interferon-gamma Production Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Transcriptional Activation By Promoter-enhancer Looping Tricuspid Valve Formation Tricuspid Valve Morphogenesis Primitive Erythrocyte Differentiation Tricuspid Valve Development Blood Coagulation Hemostasis Regulation Of Definitive Erythrocyte Differentiation Regulation Of Mast Cell Differentiation Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Mitochondrial Translation Mitral Valve Morphogenesis Definitive Erythrocyte Differentiation Organelle Assembly Cellular Localization Negative Regulation Of Interleukin-4 Production Positive Regulation Of Dendritic Cell Chemotaxis Mitral Valve Development Elastic Fiber Assembly Chromosome Organization Protein Localization To Microtubule
Tagcloud ?			accelerate advancing aging bubr1 claimed ebp ghr ghrhr gompertz insr instance interpreted klotho lmna longevity msra pit1 polga prdx1 prop1 prove retard shc1 span straightforward tables terc trx wrn
Tagcloud (Difference) ?			accelerate advancing aging bubr1 claimed ebp ghr ghrhr gompertz insr instance interpreted klotho lmna longevity msra pit1 polga prdx1 prop1 prove retard shc1 span straightforward tables terc trx wrn
Tagcloud (Intersection) ?