NR2E3 and DHX30

Number of citations of the paper that reports this interaction (PMID 17255935)
27

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		NR2E3	DHX30
Gene Name		nuclear receptor subfamily 2, group E, member 3	DEAH (Asp-Glu-Ala-His) box helicase 30
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Nucleoid
	Molecular Function	Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Chromatin Binding Double-stranded RNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Proliferation Gene Expression Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Rhodopsin Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Retina Development In Camera-type Eye	RNA Processing
Pathways
Drugs
Diseases
GWAS		Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		27 interactors: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 ZNF232	17 interactors: CDK9 DHX58 EIF2AK2 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 RBBP4 RBBP7 RBL1 SIN3A SKIL TBL3
Entrez ID		10002	22907
HPRD ID		05132	13142
Ensembl ID			ENSG00000132153
Uniprot IDs		B6ZGU0 F1D8Q9 Q9Y5X4	Q7L2E3
PDB IDs			2DB2
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway Cellular Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Circadian Regulation Of Gene Expression Circadian Rhythm Rhythmic Process Cellular Response To Steroid Hormone Stimulus Chromatin Modification Positive Regulation Of Metabolic Process Chromatin Organization Regulation Of Receptor Biosynthetic Process Response To Organic Substance	Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transforming Growth Factor Beta Receptor Signaling Pathway Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Regulation Of Gene Expression Chromatin Modification Circadian Rhythm Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Negative Regulation Of Gene Expression, Epigenetic Circadian Regulation Of Gene Expression Chromatin Organization Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Biosynthetic Process Transcription From RNA Polymerase II Promoter Viral Process Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Response To Growth Factor Chromosome Organization Regulation Of Viral Process Cellular Response To Stimulus Response To Stimulus
Tagcloud ?		11a causing compound correlates cytotoxic cytotoxicity eralpha excluding facilitate favorable hct116 hela implying isogenic mediator mutated nci null orphan p53 photoreceptor pleiotropic pnr responsive retain retinal systematic tamoxifen varying	box brains called confirm dexh died e7 e9 embryogenesis embryonic encodes gastrulation growing headfold helg helicase homozygous identifying ie mutants named neural plate polynucleotides purification retarded somites tube untwisting
Tagcloud (Difference) ?		11a causing compound correlates cytotoxic cytotoxicity eralpha excluding facilitate favorable hct116 hela implying isogenic mediator mutated nci null orphan p53 photoreceptor pleiotropic pnr responsive retain retinal systematic tamoxifen varying	box brains called confirm dexh died e7 e9 embryogenesis embryonic encodes gastrulation growing headfold helg helicase homozygous identifying ie mutants named neural plate polynucleotides purification retarded somites tube untwisting
Tagcloud (Intersection) ?