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TRAF7 - Wiki-MPM

Search Results for: TRAF7

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel BTBD1 BTB domain containing 1
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel HAGHL hydroxyacylglutathione hydrolase like
Novel HDGF heparin binding growth factor
  • XBP1(S) activates chaperone genes
  • Copper
Novel NUDT16L1 nudix hydrolase 16 like 1
Novel PBXIP1 PBX homeobox interacting protein 1
Novel PPIC peptidylprolyl isomerase C
  • Proline
CDC42 cell division cycle 42
  • GPVI-mediated activation cascade
  • EGFR downregulation
  • Rho GTPase cycle
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • CD28 dependent Vav1 pathway
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • DCC mediated attractive signaling
  • Inactivation of CDC42 and RAC1
  • VEGFA-VEGFR2 Pathway
  • Myogenesis
  • Myogenesis
  • RHO GTPases activate KTN1
  • RHO GTPases activate IQGAPs
  • RHO GTPases activate PAKs
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate Formins
  • RHO GTPases Activate Formins
  • MAPK6/MAPK4 signaling
  • Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
  • G beta:gamma signalling through CDC42
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
  • Factors involved in megakaryocyte development and platelet production
  • Aminophosphonic acid-guanylate ester
  • Guanosine-5'-Diphosphate
CYLD CYLD lysine 63 deubiquitinase
  • NOD1/2 Signaling Pathway
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NFkappaB signaling pathway
  • Ub-specific processing proteases
  • Negative regulators of DDX58/IFIH1 signaling
  • Familial cylindromatosis
  • Multiple familial trichoepithelioma
  • Brooke-Spiegler syndrome
MAP3K3 mitogen-activated protein kinase kinase kinase 3
  • Interleukin-1 signaling
  • Fostamatinib
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
  • HATs acetylate histones
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • UCH proteinases
RIPK4 receptor interacting serine/threonine kinase 4
TRAF6 TNF receptor associated factor 6
  • PIP3 activates AKT signaling
  • MyD88:MAL(TIRAP) cascade initiated on plasma membrane
  • NOD1/2 Signaling Pathway
  • TICAM1, RIP1-mediated IKK complex recruitment
  • Regulated proteolysis of p75NTR
  • Downstream TCR signaling
  • NRIF signals cell death from the nucleus
  • NRIF signals cell death from the nucleus
  • p75NTR recruits signalling complexes
  • NF-kB is activated and signals survival
  • FCERI mediated NF-kB activation
  • TAK1 activates NFkB by phosphorylation and activation of IKKs complex
  • activated TAK1 mediates p38 MAPK activation
  • JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
  • CLEC7A (Dectin-1) signaling
  • Ub-specific processing proteases
  • Ovarian tumor domain proteases
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • TICAM1,TRAF6-dependent induction of TAK1 complex
  • Interleukin-1 signaling
  • TRAF6 mediated IRF7 activation
  • TRAF6 mediated NF-kB activation
  • TRAF6 mediated NF-kB activation
  • IRAK1 recruits IKK complex
  • IKK complex recruitment mediated by RIP1
  • IRAK2 mediated activation of TAK1 complex
  • TRAF6-mediated induction of TAK1 complex within TLR4 complex
  • Alpha-protein kinase 1 signaling pathway
  • TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
  • TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
  • IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
  • MyD88 dependent cascade initiated on endosome
  • IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
  • MyD88 cascade initiated on plasma membrane
UBE2D1 ubiquitin conjugating enzyme E2 D1
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Inactivation of APC/C via direct inhibition of the APC/C complex
  • TICAM1, RIP1-mediated IKK complex recruitment
  • APC/C:Cdc20 mediated degradation of Cyclin B
  • Autodegradation of Cdh1 by Cdh1:APC/C
  • APC/C:Cdc20 mediated degradation of Securin
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • Cdc20:Phospho-APC/C mediated degradation of Cyclin A
  • Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
  • Regulation of APC/C activators between G1/S and early anaphase
  • APC/C:Cdc20 mediated degradation of mitotic proteins
  • Phosphorylation of the APC/C
  • APC-Cdc20 mediated degradation of Nek2A
  • Signaling by BMP
  • Downstream TCR signaling
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Separation of Sister Chromatids
  • Senescence-Associated Secretory Phenotype (SASP)
  • FCERI mediated NF-kB activation
  • CLEC7A (Dectin-1) signaling
  • Ovarian tumor domain proteases
  • CDK-mediated phosphorylation and removal of Cdc6
  • Transcriptional Regulation by VENTX
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Neddylation
  • Peroxisomal protein import
  • Negative regulators of DDX58/IFIH1 signaling
  • IKK complex recruitment mediated by RIP1
  • Aberrant regulation of mitotic exit in cancer due to RB1 defects
  • Antigen processing: Ubiquitination & Proteasome degradation
UBE2D2 ubiquitin conjugating enzyme E2 D2
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • TICAM1, RIP1-mediated IKK complex recruitment
  • Downstream TCR signaling
  • FCERI mediated NF-kB activation
  • CLEC7A (Dectin-1) signaling
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Neddylation
  • Peroxisomal protein import
  • Negative regulators of DDX58/IFIH1 signaling
  • IKK complex recruitment mediated by RIP1
  • Antigen processing: Ubiquitination & Proteasome degradation
  • (R,R)-2,3-Butanediol
UBE2D4 ubiquitin conjugating enzyme E2 D4 (putative)
  • Antigen processing: Ubiquitination & Proteasome degradation
UBE2K ubiquitin conjugating enzyme E2 K
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • Negative regulators of DDX58/IFIH1 signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
UBE2L3 ubiquitin conjugating enzyme E2 L3
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Antigen processing: Ubiquitination & Proteasome degradation
UBE2L6 ubiquitin conjugating enzyme E2 L6
  • ISG15 antiviral mechanism
  • DDX58/IFIH1-mediated induction of interferon-alpha/beta
  • Termination of translesion DNA synthesis
  • Negative regulators of DDX58/IFIH1 signaling
  • Negative regulators of DDX58/IFIH1 signaling
  • Amyloid fiber formation
  • Antigen processing: Ubiquitination & Proteasome degradation

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