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SUZ12 - Wiki-MPM

Search Results for: SUZ12

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ARHGAP5 Rho GTPase activating protein 5
  • Rho GTPase cycle
Novel CDK5R1 cyclin dependent kinase 5 regulatory subunit 1
  • CRMPs in Sema3A signaling
  • CRMPs in Sema3A signaling
  • Regulation of TP53 Activity through Phosphorylation
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • Activated NTRK2 signals through CDK5
  • Indirubin-3'-monoxime
  • 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE
Novel KLRC1 killer cell lectin like receptor C1
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Novel NOL4 nucleolar protein 4
Novel NR1D1 nuclear receptor subfamily 1 group D member 1
  • NR1D1 (REV-ERBA) represses gene expression
  • PPARA activates gene expression
  • Transcriptional activation of mitochondrial biogenesis
  • Nuclear Receptor transcription pathway
  • Circadian Clock
  • Circadian Clock
  • SR-9009
  • SR-9011
Novel PLA2G2A phospholipase A2 group IIA
  • Acyl chain remodelling of PC
  • Acyl chain remodelling of PS
  • Acyl chain remodelling of PE
  • Acyl chain remodelling of PI
  • Acyl chain remodelling of PG
  • Synthesis of PA
  • Antimicrobial peptides
  • Indomethacin
  • Ginkgo biloba
  • 1,4-Butanediol
  • 1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene
  • N-Tridecanoic Acid
  • [3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid
  • 4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid
  • Lauric acid
  • (1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid
  • 6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid
  • Elaidamide
  • (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate
  • KH064
  • Suramin
  • Varespladib methyl
Novel RBBP4 RB binding protein 4, chromatin remodeling factor
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • G0 and Early G1
  • Polo-like kinase mediated events
  • PRC2 methylates histones and DNA
  • Oxidative Stress Induced Senescence
  • HDACs deacetylate histones
  • PKMTs methylate histone lysines
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Regulation of TP53 Activity through Acetylation
  • Cyclin E associated events during G1/S transition
  • G1/S-Specific Transcription
  • Cyclin A:Cdk2-associated events at S phase entry
  • RNA Polymerase I Transcription Initiation
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Transcriptional Regulation by E2F6
  • HCMV Early Events
  • Potential therapeutics for SARS
Novel SLC2A2 solute carrier family 2 member 2
  • Cellular hexose transport
  • Regulation of gene expression in beta cells
  • Regulation of insulin secretion
  • Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)
  • Intestinal hexose absorption
  • Streptozocin
  • Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
Novel TBC1D29P TBC1 domain family member 29, pseudogene
AEBP2 AE binding protein 2
  • PRC2 methylates histones and DNA
  • PKMTs methylate histone lysines
BCL11A BAF chromatin remodeling complex subunit BCL11A
CDK19 cyclin dependent kinase 19
  • PPARA activates gene expression
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
CDK8 cyclin dependent kinase 8
  • PPARA activates gene expression
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Generic Transcription Pathway
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Alvocidib
CREB1 cAMP responsive element binding protein 1
  • PKA-mediated phosphorylation of CREB
  • CaMK IV-mediated phosphorylation of CREB
  • AKT phosphorylates targets in the nucleus
  • CREB phosphorylation
  • Transcriptional activation of mitochondrial biogenesis
  • Transcriptional activation of mitochondrial biogenesis
  • NOTCH2 intracellular domain regulates transcription
  • NCAM signaling for neurite out-growth
  • Circadian Clock
  • Circadian Clock
  • CREB1 phosphorylation through the activation of Adenylate Cyclase
  • CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
  • CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling
  • Constitutive Signaling by AKT1 E17K in Cancer
  • Gastrin-CREB signalling pathway via PKC and MAPK
  • Regulation of MECP2 expression and activity
  • MECP2 regulates neuronal receptors and channels
  • MECP2 regulates transcription of neuronal ligands
  • MECP2 regulates transcription factors
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • HCMV Early Events
  • Transcriptional regulation of granulopoiesis
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • ADORA2B mediated anti-inflammatory cytokines production
  • ADORA2B mediated anti-inflammatory cytokines production
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated IL10 synthesis
  • Adenosine phosphate
  • Naloxone
CTCF CCCTC-binding factor
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
  • PRC2 methylates histones and DNA
  • Oxidative Stress Induced Senescence
  • PKMTs methylate histone lysines
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Transcriptional Regulation by E2F6
  • HCMV Early Events
  • Tazemetostat
  • CPI-1205
H1-1 H1.1 linker histone, cluster member
  • Apoptosis induced DNA fragmentation
  • Formation of Senescence-Associated Heterochromatin Foci (SAHF)
H3-4 H3.4 histone
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Formation of the beta-catenin:TCF transactivating complex
  • Formation of the beta-catenin:TCF transactivating complex
  • Condensation of Prophase Chromosomes
  • DNA Damage/Telomere Stress Induced Senescence
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • G2/M DNA damage checkpoint
  • Meiotic recombination
  • Inhibition of DNA recombination at telomere
LATS2 large tumor suppressor kinase 2
  • Signaling by Hippo
MED17 mediator complex subunit 17
  • PPARA activates gene expression
  • Generic Transcription Pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation

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