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SMARCB1 - Wiki-MPM

Search Results for: SMARCB1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel CNTNAP3 contactin associated protein family member 3
Novel MYO18B myosin XVIIIB
Novel VPREB3 V-set pre-B cell surrogate light chain 3
  • Cell surface interactions at the vascular wall
ABI2 abl interactor 2
  • Regulation of actin dynamics for phagocytic cup formation
  • Regulation of actin dynamics for phagocytic cup formation
  • VEGFA-VEGFR2 Pathway
  • RHO GTPases Activate WASPs and WAVEs
  • RHO GTPases Activate WASPs and WAVEs
  • FCGR3A-mediated phagocytosis
  • FCGR3A-mediated phagocytosis
AKT1 AKT serine/threonine kinase 1
  • Activation of BAD and translocation to mitochondria
  • PIP3 activates AKT signaling
  • PIP3 activates AKT signaling
  • Downregulation of ERBB2:ERBB3 signaling
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
  • MTOR signalling
  • AKT phosphorylates targets in the cytosol
  • AKT phosphorylates targets in the cytosol
  • AKT phosphorylates targets in the nucleus
  • Negative regulation of the PI3K/AKT network
  • eNOS activation
  • AKT-mediated inactivation of FOXO1A
  • Integrin signaling
  • Deactivation of the beta-catenin transactivating complex
  • CD28 dependent PI3K/Akt signaling
  • CTLA4 inhibitory signaling
  • G beta:gamma signalling through PI3Kgamma
  • Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
  • KSRP (KHSRP) binds and destabilizes mRNA
  • VEGFR2 mediated vascular permeability
  • TP53 Regulates Metabolic Genes
  • Constitutive Signaling by AKT1 E17K in Cancer
  • Interleukin-4 and Interleukin-13 signaling
  • Regulation of TP53 Degradation
  • Regulation of TP53 Activity through Acetylation
  • Regulation of TP53 Activity through Association with Co-factors
  • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • Cyclin E associated events during G1/S transition
  • Cyclin A:Cdk2-associated events at S phase entry
  • PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
  • RAB GEFs exchange GTP for GDP on RABs
  • RUNX2 regulates genes involved in cell migration
  • Regulation of PTEN stability and activity
  • Extra-nuclear estrogen signaling
  • Negative regulation of NOTCH4 signaling
  • FLT3 Signaling
  • Regulation of localization of FOXO transcription factors
  • Estrogen-dependent nuclear events downstream of ESR-membrane signaling
  • ATP
  • Arsenic trioxide
  • Genistein
  • Inositol 1,3,4,5-Tetrakisphosphate
  • Resveratrol
  • Archexin
  • Enzastaurin
  • Perifosine
  • N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
  • PTEN hamartoma tumor syndrome (PHTS), including: Cowden syndrome; Bannayan-Riley-Ruvalcaba syndrome; Proteus syndrome; Proteus-like syndrome
APP amyloid beta precursor protein
  • Platelet degranulation
  • ECM proteoglycans
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • G alpha (q) signalling events
  • G alpha (i) signalling events
  • Lysosome Vesicle Biogenesis
  • Formyl peptide receptors bind formyl peptides and many other ligands
  • TAK1 activates NFkB by phosphorylation and activation of IKKs complex
  • The NLRP3 inflammasome
  • Advanced glycosylation endproduct receptor signaling
  • Advanced glycosylation endproduct receptor signaling
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • Post-translational protein phosphorylation
  • TRAF6 mediated NF-kB activation
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
  • Purinergic signaling in leishmaniasis infection
  • Amyloid fiber formation
  • Deferoxamine
  • Aluminium
  • Zinc
  • L-methionine (R)-S-oxide
  • Resveratrol
  • Tromethamine
  • Phenserine
  • Tetrathiomolybdate
  • CAD106
  • Mito-4509
  • Edonerpic
  • Dimercaprol
  • Copper
  • Florbetaben (18F)
  • Florbetapir (18F)
  • Flutemetamol (18F)
  • Zinc acetate
  • Aluminium phosphate
  • Aluminum acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
  • Alzheimer's disease (AD)
ARL11 ADP ribosylation factor like GTPase 11
ATP5F1A ATP synthase F1 subunit alpha
  • Mitochondrial protein import
  • Formation of ATP by chemiosmotic coupling
  • Cristae formation
  • Quercetin
  • 1-ACETYL-2-CARBOXYPIPERIDINE
  • AUROVERTIN B
  • Piceatannol
  • N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
  • Artenimol
BCL2L11 BCL2 like 11
  • Activation of BIM and translocation to mitochondria
  • BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
  • NRAGE signals death through JNK
  • Signaling by BRAF and RAF fusions
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • RUNX3 regulates BCL2L11 (BIM) transcription
  • FLT3 Signaling
  • FOXO-mediated transcription of cell death genes
BHLHE40 basic helix-loop-helix family member e40
  • BMAL1:CLOCK,NPAS2 activates circadian gene expression
BLZF1 basic leucine zipper nuclear factor 1
  • Golgi Cisternae Pericentriolar Stack Reorganization
CALR calreticulin
  • ER-Phagosome pathway
  • Assembly of Viral Components at the Budding Site
  • Scavenging by Class A Receptors
  • Scavenging by Class A Receptors
  • Scavenging by Class F Receptors
  • Scavenging by Class F Receptors
  • ATF6 (ATF6-alpha) activates chaperone genes
  • Calnexin/calreticulin cycle
  • Antigen Presentation: Folding, assembly and peptide loading of class I MHC
  • Antihemophilic factor, human recombinant
  • Tenecteplase
  • Melatonin
  • Lanoteplase
  • Copper
  • Calcium citrate
  • Calcium Phosphate
  • Lonoctocog alfa
  • Moroctocog alfa
  • Calcium phosphate dihydrate
CAMK2D calcium/calmodulin dependent protein kinase II delta
  • CaMK IV-mediated phosphorylation of CREB
  • HSF1-dependent transactivation
  • Trafficking of AMPA receptors
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Unblocking of NMDA receptors, glutamate binding and activation
  • Ras activation upon Ca2+ influx through NMDA receptor
  • Phase 0 - rapid depolarisation
  • Ion homeostasis
  • RAF activation
  • RAF/MAP kinase cascade
  • Signaling by moderate kinase activity BRAF mutants
  • Signaling by BRAF and RAF fusions
  • Paradoxical activation of RAF signaling by kinase inactive BRAF
  • Interferon gamma signaling
  • Regulation of MECP2 expression and activity
  • Ion transport by P-type ATPases
  • Assembly and cell surface presentation of NMDA receptors
  • Negative regulation of NMDA receptor-mediated neuronal transmission
  • Long-term potentiation
  • Signaling downstream of RAS mutants
  • Signaling by RAF1 mutants
  • 2-[4-[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]iminocyclohexa-2,5-dien-1-yl]acetonitrile
  • (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
  • Fostamatinib
CCDC120 coiled-coil domain containing 120
CCDC33 coiled-coil domain containing 33
CD69 CD69 molecule
CDC23 cell division cycle 23
  • Inactivation of APC/C via direct inhibition of the APC/C complex
  • APC/C:Cdc20 mediated degradation of Cyclin B
  • Autodegradation of Cdh1 by Cdh1:APC/C
  • APC/C:Cdc20 mediated degradation of Securin
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • Cdc20:Phospho-APC/C mediated degradation of Cyclin A
  • Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
  • Regulation of APC/C activators between G1/S and early anaphase
  • APC/C:Cdc20 mediated degradation of mitotic proteins
  • Phosphorylation of the APC/C
  • APC-Cdc20 mediated degradation of Nek2A
  • Separation of Sister Chromatids
  • Senescence-Associated Secretory Phenotype (SASP)
  • CDK-mediated phosphorylation and removal of Cdc6
  • Transcriptional Regulation by VENTX
  • Aberrant regulation of mitotic exit in cancer due to RB1 defects
  • Antigen processing: Ubiquitination & Proteasome degradation
CDX2 caudal type homeobox 2
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
CEBPB CCAAT enhancer binding protein beta
  • Senescence-Associated Secretory Phenotype (SASP)
  • Senescence-Associated Secretory Phenotype (SASP)
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional Regulation by VENTX
  • Transcriptional regulation of granulopoiesis
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
  • Quercetin
CHFR checkpoint with forkhead and ring finger domains

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