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NR2F2 - Wiki-MPM

Search Results for: NR2F2

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel CHD2 chromodomain helicase DNA binding protein 2
Novel RLBP1 retinaldehyde binding protein 1
  • The retinoid cycle in cones (daylight vision)
  • The retinoid cycle in cones (daylight vision)
  • Retinoid cycle disease events
  • The canonical retinoid cycle in rods (twilight vision)
  • Newfoundland rod-cone dystrophy (NFRCD)
  • Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
Novel SYCP3 synaptonemal complex protein 3
  • Meiotic synapsis
  • Azoospermia, including: Azoospermia; Azoospermia due to perturbations of meiosis
BCL11A BAF chromatin remodeling complex subunit BCL11A
BCL11B BAF chromatin remodeling complex subunit BCL11B
BIK BCL2 interacting killer
EP300 E1A binding protein p300
  • Regulation of gene expression by Hypoxia-inducible Factor
  • RORA activates gene expression
  • Polo-like kinase mediated events
  • Pre-NOTCH Transcription and Translation
  • Pre-NOTCH Transcription and Translation
  • PPARA activates gene expression
  • PPARA activates gene expression
  • Formation of the beta-catenin:TCF transactivating complex
  • Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
  • NOTCH1 Intracellular Domain Regulates Transcription
  • NOTCH1 Intracellular Domain Regulates Transcription
  • NOTCH2 intracellular domain regulates transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
  • HATs acetylate histones
  • Attenuation phase
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • SUMOylation of transcription cofactors
  • Circadian Clock
  • B-WICH complex positively regulates rRNA expression
  • Activation of anterior HOX genes in hindbrain development during early embryogenesis
  • CD209 (DC-SIGN) signaling
  • Metalloprotease DUBs
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
  • Regulation of TP53 Activity through Acetylation
  • Regulation of TP53 Activity through Methylation
  • PI5P Regulates TP53 Acetylation
  • Activation of the TFAP2 (AP-2) family of transcription factors
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • RUNX3 regulates NOTCH signaling
  • RUNX3 regulates NOTCH signaling
  • Regulation of RUNX3 expression and activity
  • RUNX3 regulates p14-ARF
  • NOTCH3 Intracellular Domain Regulates Transcription
  • NOTCH3 Intracellular Domain Regulates Transcription
  • NOTCH4 Intracellular Domain Regulates Transcription
  • Estrogen-dependent gene expression
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • NGF-stimulated transcription
  • NGF-stimulated transcription
  • TRAF3-dependent IRF activation pathway
  • TRAF6 mediated IRF7 activation
  • FOXO-mediated transcription of cell death genes
  • Transcriptional regulation of granulopoiesis
  • Transcriptional regulation of granulopoiesis
  • Regulation of FOXO transcriptional activity by acetylation
  • Regulation of FOXO transcriptional activity by acetylation
  • Rubinstein-Taybi syndrome
HDAC1 histone deacetylase 1
  • Transcription of E2F targets under negative control by DREAM complex
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • G0 and Early G1
  • p75NTR negatively regulates cell cycle via SC1
  • Formation of the beta-catenin:TCF transactivating complex
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • HDACs deacetylate histones
  • Notch-HLH transcription pathway
  • Deactivation of the beta-catenin transactivating complex
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • NoRC negatively regulates rRNA expression
  • SUMOylation of chromatin organization proteins
  • Repression of WNT target genes
  • Repression of WNT target genes
  • Regulation of TP53 Activity through Acetylation
  • G1/S-Specific Transcription
  • RNA Polymerase I Transcription Initiation
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Estrogen-dependent gene expression
  • Loss of MECP2 binding ability to 5mC-DNA
  • Regulation of MECP2 expression and activity
  • MECP2 regulates neuronal receptors and channels
  • MECP2 regulates transcription of neuronal ligands
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Potential therapeutics for SARS
  • Factors involved in megakaryocyte development and platelet production
  • Arsenic trioxide
  • Zinc
  • Vorinostat
  • Belinostat
  • Pracinostat
  • Romidepsin
  • Panobinostat
  • Fingolimod
  • Mocetinostat
  • Abexinostat
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
HIPK3 homeodomain interacting protein kinase 3
  • Fostamatinib
MYOD1 myogenic differentiation 1
  • Myogenesis
  • Myogenesis
NCOR2 nuclear receptor corepressor 2
  • PPARA activates gene expression
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • HDACs deacetylate histones
  • Notch-HLH transcription pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Nuclear Receptor transcription pathway
  • SUMOylation of transcription cofactors
  • Regulation of lipid metabolism by PPARalpha
  • Loss of MECP2 binding ability to the NCoR/SMRT complex
  • Regulation of MECP2 expression and activity
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • HCMV Early Events
  • NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
NR2F6 nuclear receptor subfamily 2 group F member 6
  • Nuclear Receptor transcription pathway
NR3C1 nuclear receptor subfamily 3 group C member 1
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • Circadian Clock
  • SUMOylation of intracellular receptors
  • PTK6 Expression
  • Regulation of RUNX2 expression and activity
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Potential therapeutics for SARS
  • Flunisolide
  • Diflorasone
  • Alclometasone
  • Medrysone
  • Amcinonide
  • Fluorometholone
  • Megestrol acetate
  • Levonorgestrel
  • Beclomethasone dipropionate
  • Progesterone
  • Spironolactone
  • Betamethasone
  • Desoximetasone
  • Fluticasone propionate
  • Fluocinolone acetonide
  • Ulobetasol
  • Triamcinolone
  • Prednisone
  • Flumethasone
  • Fludrocortisone
  • Norethisterone
  • Hydrocortisone
  • Mometasone
  • Hydrocortamate
  • Mifepristone
  • Clocortolone
  • Flurandrenolide
  • Prednisolone
  • Loteprednol etabonate
  • Rimexolone
  • Methylprednisolone
  • Clobetasol propionate
  • Fluocinonide
  • Prednicarbate
  • Fluoxymesterone
  • Budesonide
  • Dexamethasone
  • Desonide
  • Cortisone acetate
  • Paramethasone
  • Drospirenone
  • Ciclesonide
  • Hexane-1,6-Diol
  • Aldosterone
  • ORG-34517
  • Difluprednate
  • Ulipristal
  • Fluticasone furoate
  • Tixocortol
  • Difluocortolone
  • Gestrinone
  • Deflazacort
  • Onapristone
  • Cortivazol
  • Clobetasone
  • Fluticasone
  • Mometasone furoate
  • Hydrocortisone aceponate
  • Hydrocortisone acetate
  • Hydrocortisone butyrate
  • Hydrocortisone cypionate
  • Hydrocortisone phosphate
  • Hydrocortisone probutate
  • Hydrocortisone valerate
  • Segesterone acetate
  • Prednisolone phosphate
  • Dexamethasone acetate
  • Betamethasone phosphate
  • Prednisolone acetate
  • 46,XX disorders of sex development (Disorders related to androgen excess), including: Congenital adrenal hyperplasias; Glucocorticoid resistance; Aromatase deficiency
NSD1 nuclear receptor binding SET domain protein 1
  • PKMTs methylate histone lysines
  • Beckwith-Wiedemann syndrome
  • Sotos syndrome and Weaver syndrome
PHB2 prohibitin 2
  • Processing of SMDT1
  • Capsaicin
  • Rocaglamide
  • Didesmethylrocaglamide
PIAS1 protein inhibitor of activated STAT 1
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of transcription factors
  • SUMOylation of ubiquitinylation proteins
  • SUMOylation of transcription cofactors
  • SUMOylation of intracellular receptors
  • SUMOylation of intracellular receptors
  • SUMOylation of chromatin organization proteins
  • Formation of Incision Complex in GG-NER
  • Regulation of IFNG signaling
SETD7 SET domain containing 7, histone lysine methyltransferase
  • PKMTs methylate histone lysines
  • S-adenosyl-L-homocysteine
SQSTM1 sequestosome 1
  • NRIF signals cell death from the nucleus
  • p75NTR recruits signalling complexes
  • NF-kB is activated and signals survival
  • PINK1-PRKN Mediated Mitophagy
  • Interleukin-1 signaling
  • Pexophagy
  • Paget's disease of bone and related disorders, including: ; Paget's disease of bone (PDB); Familial expansile osteolysis (FEO); Early-onset Paget's disease of bone (PDB2); Expansile skeletal hyperphosphatasia (ESH); Juvenile Paget's disease (JPD)
TENT5A terminal nucleotidyltransferase 5A
TRIM24 tripartite motif containing 24
  • Signaling by cytosolic FGFR1 fusion mutants
  • Signaling by FGFR1 in disease
  • Signaling by BRAF and RAF fusions

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