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IGKC - Wiki-MPM

Search Results for: IGKC

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel PLGLB2 plasminogen like B2
Novel REG3A regenerating family member 3 alpha
  • Antimicrobial peptides
CD40LG CD40 ligand
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • TNFR2 non-canonical NF-kB pathway
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ruplizumab
  • Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
MLH1 mutL homolog 1
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • Defective Mismatch Repair Associated With MLH1
  • Defective Mismatch Repair Associated With PMS2
  • TP53 Regulates Transcription of DNA Repair Genes
  • Meiotic recombination
  • Colorectal cancer
  • Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
  • Endometrial Cancer
  • Ovarian cancer
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known

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