EGFR - Wiki-MPM

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	HEBP1	heme binding protein 1	G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands
Novel	PHKG1	phosphorylase kinase catalytic subunit gamma 1	Glycogen breakdown (glycogenolysis) Glycogen breakdown (glycogenolysis)	Fostamatinib
Novel	POM121L12	POM121 transmembrane nucleoporin like 12
Novel	STAG3L4	stromal antigen 3-like 4 (pseudogene)
	ABL2	ABL proto-oncogene 2, non-receptor tyrosine kinase	Role of ABL in ROBO-SLIT signaling Role of ABL in ROBO-SLIT signaling Negative regulation of FLT3	ATP Dasatinib XL228 K-00546 Fostamatinib
	ACTA1	actin alpha 1, skeletal muscle	Striated Muscle Contraction	Latrunculin A Sucrose Ulapualide A Kabiramide C Jaspisamide A Tmr 1-Methylhistidine Phosphoaminophosphonic Acid-Adenylate Ester Aplyronine A Reidispongiolide A Reidispongiolide C Sphinxolide B Latrunculin B	Congenital fiber type disproportion (CFTD) Cap myopathy Nemaline myopathy
	ADRM1	adhesion regulating molecule 1	UCH proteinases Ub-specific processing proteases
	AGTR1	angiotensin II receptor type 1	Peptide ligand-binding receptors G alpha (q) signalling events Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Valsartan Olmesartan Losartan Candesartan cilexetil Eprosartan Telmisartan Irbesartan Forasartan Saprisartan Tasosartan CYT006-AngQb Azilsartan medoxomil Fimasartan Angiotensin II Candesartan	Renal tubular dysgenesis
	AHNAK	AHNAK nucleoprotein
	AHSA1	activator of HSP90 ATPase activity 1
	AIP	aryl hydrocarbon receptor interacting protein	Aryl hydrocarbon receptor signalling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
	AKAP12	A-kinase anchoring protein 12
	ALCAM	activated leukocyte cell adhesion molecule	L1CAM interactions
	ALDOA	aldolase, fructose-bisphosphate A	Platelet degranulation Neutrophil degranulation Glycolysis Gluconeogenesis	Zinc 1,6-Fructose Diphosphate (Linear Form) Dihydroxyacetone phosphate 1,6-DI-O-PHOSPHONO-D-MANNITOL N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
	AMH	anti-Mullerian hormone	Signaling by BMP Transcriptional regulation of testis differentiation		46,XY disorders of sex development (Other), including: Persistent Mullerian duct syndrome; Hypospadias; Cryptorchidism
	ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A
	ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B
	ANXA1	annexin A1	G alpha (q) signalling events G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Smooth Muscle Contraction Interleukin-4 and Interleukin-13 signaling	Amcinonide Fluocinolone acetonide Hydrocortisone Methylprednisolone Clobetasol propionate Budesonide Dexamethasone Hydrocortisone aceponate Hydrocortisone acetate Hydrocortisone butyrate Hydrocortisone cypionate Hydrocortisone phosphate Hydrocortisone probutate Hydrocortisone valerate Prednisolone phosphate Dexamethasone acetate Betamethasone phosphate
	AOPEP	aminopeptidase O (putative)	Metabolism of Angiotensinogen to Angiotensins
	AP2B1	adaptor related protein complex 2 subunit beta 1	Nef Mediated CD4 Down-regulation Retrograde neurotrophin signalling Retrograde neurotrophin signalling Nef Mediated CD8 Down-regulation MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Recycling pathway of L1 WNT5A-dependent internalization of FZD4 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis VLDLR internalisation and degradation LDL clearance Potential therapeutics for SARS

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