Search Results for: ATXN1

292 interactions involving ATXN1 - ataxin 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
SLC25A51 solute carrier family 25 member 51
SLC4A2 solute carrier family 4 member 2
  • Bicarbonate transporters
SLC51A solute carrier family 51 subunit alpha
SLC6A13 solute carrier family 6 member 13
  • Na+/Cl- dependent neurotransmitter transporters
  • Reuptake of GABA
  • Guvacine
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
SORCS3 sortilin related VPS10 domain containing receptor 3
SOX3 SRY-box transcription factor 3
  • Deactivation of the beta-catenin transactivating complex
  • Septo-optic dysplasia
  • Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
  • 46,XX disorders of sex development (Disorders of gonadal development), including: Ovotesticular DSD; Testicular DSD; Ovarian dysgenesis
  • Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
SPEN spen family transcriptional repressor
SREBF1 sterol regulatory element binding transcription factor 1
  • RORA activates gene expression
  • FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
  • Doconexent
  • Omega-3-acid ethyl esters
  • Omega-3 fatty acids
  • Fish oil
SREBF2 sterol regulatory element binding transcription factor 2
  • Regulation of cholesterol biosynthesis by SREBP (SREBF)
  • Regulation of cholesterol biosynthesis by SREBP (SREBF)
  • PPARA activates gene expression
  • Activation of gene expression by SREBF (SREBP)
  • Activation of gene expression by SREBF (SREBP)
  • Transcriptional regulation of white adipocyte differentiation
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
  • Sialic acid metabolism
  • Lewis blood group biosynthesis
STAC2 SH3 and cysteine rich domain 2
STAM2 signal transducing adaptor molecule 2
  • EGFR downregulation
  • Ub-specific processing proteases
  • Negative regulation of MET activity
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • InlB-mediated entry of Listeria monocytogenes into host cell
  • Endosomal Sorting Complex Required For Transport (ESCRT)
SUGP2 SURP and G-patch domain containing 2
SUMO1 small ubiquitin like modifier 1
  • SUMO is conjugated to E1 (UBA2:SAE1)
  • SUMO is transferred from E1 to E2 (UBE2I, UBC9)
  • SUMO is proteolytically processed
  • SUMOylation of DNA damage response and repair proteins
  • SUMO E3 ligases SUMOylate target proteins
  • SUMOylation of transcription factors
  • SUMOylation of transcription factors
  • SUMOylation of ubiquitinylation proteins
  • SUMOylation of transcription cofactors
  • SUMOylation of transcription cofactors
  • SUMOylation of SUMOylation proteins
  • SUMOylation of intracellular receptors
  • SUMOylation of intracellular receptors
  • SUMOylation of chromatin organization proteins
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of DNA methylation proteins
  • SUMOylation of DNA methylation proteins
  • SUMOylation of immune response proteins
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Nonhomologous End-Joining (NHEJ)
  • Processing of DNA double-strand break ends
  • Formation of Incision Complex in GG-NER
  • G2/M DNA damage checkpoint
  • Regulation of IFNG signaling
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Negative regulation of activity of TFAP2 (AP-2) family transcription factors
  • Postmitotic nuclear pore complex (NPC) reformation
  • Maturation of nucleoprotein
  • Maturation of nucleoprotein
SUPT20H SPT20 homolog, SAGA complex component
  • HATs acetylate histones
SV2A synaptic vesicle glycoprotein 2A
  • Toxicity of botulinum toxin type D (botD)
  • Toxicity of botulinum toxin type A (botA)
  • Toxicity of botulinum toxin type F (botF)
  • Toxicity of botulinum toxin type E (botE)
  • Levetiracetam
  • Brivaracetam
  • Seletracetam
SYBU syntabulin
TBC1D5 TBC1 domain family member 5
TBX15 T-box transcription factor 15
  • Cousin syndrome

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