PUM3 and SLC7A9

Data Source:
BioGRID (affinity chromatography technology)

		PUM3	SLC7A9
Description		pumilio RNA binding family member 3	solute carrier family 7 member 9
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Endoplasmic Reticulum	Plasma Membrane Integral Component Of Plasma Membrane Apical Plasma Membrane Brush Border Membrane
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding	Protein Binding Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Regulation Of Translation Regulation Of Protein ADP-ribosylation	Amino Acid Transmembrane Transport Amino Acid Transport Neutral Amino Acid Transport L-cystine Transport Leukocyte Migration Protein-containing Complex Assembly L-alpha-amino Acid Transmembrane Transport
Pathways			Basigin interactions Amino acid transport across the plasma membrane Defective SLC3A1 causes cystinuria (CSNU) Defective SLC7A9 causes cystinuria (CSNU)
Drugs
Diseases			Cystinuria
GWAS		Depression ( 29700475) Waist circumference adjusted for body mass index ( 28552196)	Blood metabolite levels ( 24816252) Chronic kidney disease ( 20383146) Creatinine levels ( 31015462 29403010 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Fractional excretion of metabolites in chronic kidney disease ( 29545352) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Urate levels ( 31578528) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 21572414) Urinary metabolites (H-NMR features) ( 24586186)
Interacting Genes		4 interacting genes: APP CALM1 HPS6 ITGB1BP2	3 interacting genes: CREB3 HSPB1 TGM2
Entrez ID		9933	11136
HPRD ID		08822	04997
Ensembl ID		ENSG00000080608	ENSG00000021488
Uniprot IDs		Q15397	P82251
PDB IDs		4WZR 4WZW	6LI9 6LID
Enriched GO Terms of Interacting Partners?
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