PUM3 and RCL1

Data Source:
BioGRID (biochemical)

		PUM3	RCL1
Description		pumilio RNA binding family member 3	RNA terminal phosphate cyclase like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Endoplasmic Reticulum	Nucleoplasm Nucleolus
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding	Endoribonuclease Activity Protein Binding
	Biological Process	Regulation Of Translation Regulation Of Protein ADP-ribosylation	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Biological_process
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Depression ( 29700475) Waist circumference adjusted for body mass index ( 28552196)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 23263863 29403010 32888494 20139978 27863252 28017375 19862010) Mean corpuscular volume ( 23263863 29403010 32888494 20139978 27863252 28017375 19862010) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) Platelet count ( 26805783 22139419 24026423 23263863 29403010 31194788 32888494 20139978 27863252) Plateletcrit ( 32888494 27863252) Red blood cell count ( 29403010 32888494 27863252 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		4 interacting genes: APP CALM1 HPS6 ITGB1BP2	1 interacting genes: GOLGA2
Entrez ID		9933	10171
HPRD ID		08822	10189
Ensembl ID		ENSG00000080608	ENSG00000120158
Uniprot IDs		Q15397	Q5VZU3 Q9Y2P8
PDB IDs		4WZR 4WZW
Enriched GO Terms of Interacting Partners?
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