LPGAT1 and ATP6V1A

Data Source:
BioGRID (affinity chromatography technology)

		LPGAT1	ATP6V1A
Description		lysophosphatidylglycerol acyltransferase 1	ATPase H+ transporting V1 subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Integral Component Of Membrane	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting V-type ATPase, V1 Domain Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	2-acylglycerol O-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Lysophospholipid Acyltransferase Activity	ATP Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Phospholipid Biosynthetic Process Triglyceride Biosynthetic Process Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Positive Regulation Of Fatty Acid Biosynthetic Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels Phagosome Acidification Proton Transmembrane Transport
Pathways		Acyl chain remodelling of PG	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Alendronic acid Etidronic acid Tiludronic acid Bafilomycin A1 Bafilomycin B1
Diseases
GWAS		Major depressive disorder (unexposed to adversity) ( 29495898) Mean reticulocyte volume ( 32888494) Stearic acid (18:0) levels ( 23362303)	Prostate cancer ( 23535732)
Interacting Genes			6 interacting genes: ANXA7 CDC42 CDKN1A SMN1 TK1 TUFM
Entrez ID		9926	523
HPRD ID		14304	06120
Ensembl ID		ENSG00000123684	ENSG00000114573
Uniprot IDs		Q92604	P38606
PDB IDs
Enriched GO Terms of Interacting Partners?
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