TRANK1 and ANO10

Data Source:
BioGRID (two hybrid)

		TRANK1	ANO10
Description		tetratricopeptide repeat and ankyrin repeat containing 1	anoctamin 10
Image		No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function		Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity
	Biological Process		Cation Transport Chloride Transport Ion Transmembrane Transport Transmembrane Transport Cation Transmembrane Transport Chloride Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 22182935 28115744 24618891 31043756 28072414 27329760) Bipolar disorder with mood-incongruent psychosis ( 23092984) Bipolar I disorder ( 31043756) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Iris color (L* coordinate) ( 29109912) Mean platelet volume ( 32888494) Morning person ( 30696823) Platelet distribution width ( 27863252) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Schizophrenia or bipolar disorder ( 24280982) Subjective response to lithium treatment ( 26503763) Triglycerides ( 30275531)	Gastroesophageal reflux disease ( 31527586) Obesity-related traits ( 23251661) Primary central nervous system lymphoma ( 31102405)
Interacting Genes			1 interacting genes: HTR4
Entrez ID		9881	55129
HPRD ID		19247	07667
Ensembl ID		ENSG00000168016	ENSG00000160746
Uniprot IDs		A0A2R8YEM9 O15050	A0A024R2S0 Q9NW15
PDB IDs			5OC9 6R65 6R7X 6R7Y 6R7Z
Enriched GO Terms of Interacting Partners?
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