DHX38 and BCO1

Data Source:
HPRD (in vitro, in vivo)

		DHX38	BCO1
Description		DEAH-box helicase 38	beta-carotene oxygenase 1
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome	Cytosol
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding	Beta-carotene 15,15'-monooxygenase Activity Carotenoid Dioxygenase Activity Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing	Retinoid Metabolic Process Carotene Catabolic Process Vitamin A Biosynthetic Process Retinol Metabolic Process Retinal Metabolic Process Beta-carotene Metabolic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Retinoid metabolism and transport
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 28240269 23696881) Cholesterol, total ( 25961943 20686565) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 25961943 20686565) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		8 interacting genes: CDC40 CSNK2A1 MFAP1 PPP4C SNRNP200 TERF2IP U2AF1 WBP4
Entrez ID		9785	53630
HPRD ID		05720	12042
Ensembl ID		ENSG00000140829	ENSG00000135697
Uniprot IDs		Q92620	Q9HAY6
PDB IDs		5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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