GDF15 and SULT2A1

Data Source:
BioGRID (affinity chromatography technology)

		GDF15	SULT2A1
Description		growth differentiation factor 15	sulfotransferase family 2A member 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Golgi Apparatus Collagen-containing Extracellular Matrix Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	Cytokine Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity BMP Receptor Binding	Alcohol Sulfotransferase Activity Protein Binding Sulfotransferase Activity Bile-salt Sulfotransferase Activity Steroid Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding
	Biological Process	Activation Of MAPK Activity Reduction Of Food Intake In Response To Dietary Excess Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation BMP Signaling Pathway Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase B Signaling SMAD Protein Signal Transduction Negative Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Myoblast Fusion	Ethanol Catabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Catabolic Process Regulation Of Lipid Metabolic Process Bile Acid Catabolic Process Thyroid Hormone Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways			Cytosolic sulfonation of small molecules PPARA activates gene expression
Drugs			Adenosine 3',5'-diphosphate Aetiocholanolone Mercuric iodide
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058) Coffee consumption ( 31046077) Growth differentiation factor-15 levels ( 29628937) Hyperemesis gravidarum ( 29563502) Severity of nausea and vomiting of pregnancy ( 29563502)	Apolipoprotein A1 levels ( 32203549) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 30072576) Cleft palate ( 30452639) Dehydroepiandrosterone sulphate levels ( 21533175) Gallstone disease ( 30504769 27094239) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Triglyceride levels ( 32203549) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		7 interacting genes: CBX3 HOXA1 KRTAP12-2 MAPK14 MDFI NLGN3 TACC3	6 interacting genes: NIF3L1 PRDX4 STAT3 STK3 SULT1B1 TMX1
Entrez ID		9518	6822
HPRD ID		05608	00502
Ensembl ID		ENSG00000130513	ENSG00000105398
Uniprot IDs		Q99988	A8K015 Q06520
PDB IDs		5VT2 5VZ3 5VZ4 6Q2J	1EFH 1J99 1OV4 2QP3 2QP4 3F3Y 4IFB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?