KIF23 and NMB

Data Source:
BioGRID (two hybrid)

		KIF23	NMB
Description		kinesin family member 23	neuromedin B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Spindle Cytosol Kinesin Complex Microtubule Focal Adhesion Midbody Mitotic Spindle Flemming Body Centralspindlin Complex	Extracellular Region Neuron Projection
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuromedin B Receptor Binding
	Biological Process	Mitotic Spindle Elongation Mitotic Cytokinesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Glucose Homeostasis Positive Regulation Of Hormone Secretion Negative Regulation Of Hormone Secretion Arachidonic Acid Secretion
Pathways		MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Rheumatoid arthritis (ACPA-positive) ( 24532676)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Creatine kinase levels ( 29403010) P wave terminal force ( 28794112) Schizophrenia ( 29483656)
Interacting Genes		13 interacting genes: ACTA1 ARF3 CLK1 LATS2 PLK1 PPP1CB RACGAP1 RBM34 SUMO2 USP8 YWHAB YWHAG YWHAQ	4 interacting genes: BIRC2 GADD45G NMBR TPP1
Entrez ID		9493	4828
HPRD ID		05455	01210
Ensembl ID		ENSG00000137807	ENSG00000197696
Uniprot IDs		Q02241	P08949
PDB IDs		3VHX	1C98 1C9A
Enriched GO Terms of Interacting Partners?
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