HTRA3 and JAKMIP1

		HTRA3	JAKMIP1
Description		HtrA serine peptidase 3	janus kinase and microtubule interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Cytoplasm Microtubule Microtubule Cytoskeleton Extrinsic Component Of Membrane Ribonucleoprotein Complex
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Protein Binding Insulin-like Growth Factor Binding Serine-type Peptidase Activity Identical Protein Binding	RNA Binding Protein Binding Microtubule Binding Kinase Binding GABA Receptor Binding
	Biological Process	Proteolysis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway	Protein Transport Cognition
Pathways
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)	Coronary artery disease in type 1 diabetes ( 29695241) Response to angiotensin II receptor blocker therapy ( 22566498) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
Interacting Genes			19 interacting genes: BLK C18orf25 CBX8 CHRM3 DDX6 ENKD1 GABBR1 IL16 JAK1 MCRS1 MRPL11 PSMB1 SCNM1 TSGA10IP TYK2 USP2 YES1 YWHAG ZNHIT2
Entrez ID		94031	152789
HPRD ID		08821	11292
Ensembl ID		ENSG00000170801	ENSG00000152969
Uniprot IDs		P83110	B3KWB6 Q96N16
PDB IDs		2P3W 4RI0
Enriched GO Terms of Interacting Partners?
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