PGAP3 and ZPBP2

Data Source:
BioGRID (proximity labelling technology)

		PGAP3	ZPBP2
Description		post-GPI attachment to proteins phospholipase 3	zona pellucida binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane Intrinsic Component Of Endoplasmic Reticulum Membrane	Acrosomal Vesicle Zona Pellucida Receptor Complex Extracellular Region Nucleus Cell Body
	Molecular Function	Protein Binding Hydrolase Activity, Acting On Ester Bonds
	Biological Process	GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process	Acrosome Assembly Negative Regulation Of Immunoglobulin Production Sphingolipid Metabolic Process Binding Of Sperm To Zona Pellucida Circadian Regulation Of Gene Expression Membrane Lipid Catabolic Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851 31619474 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Triglyceride levels ( 30108155)	Adult asthma ( 30787307) Allergic rhinitis ( 30013184) Asthma ( 31959851 27182965 31619474 28461288) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 29273806) Asthma (time to onset) ( 27130862) Asthma or allergic disease (pleiotropy) ( 29785011) Atrial fibrillation ( 30061737 29892015) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908 21102463) Fractional exhaled nitric oxide (childhood) ( 24315451) Inflammatory bowel disease ( 28067908 23128233) Neurociticism ( 29500382) Primary biliary cholangitis ( 23000144 20639880 30643196) Primary biliary cirrhosis ( 22961000) Refractive error ( 32231278) Rheumatoid arthritis ( 30572963) Subcutaneous adipose tissue ( 27918534) Systemic sclerosis ( 30572963) Ulcerative colitis ( 28067908 20228799 21297633)
Interacting Genes
Entrez ID		93210	124626
HPRD ID		15118	18365
Ensembl ID		ENSG00000161395	ENSG00000186075
Uniprot IDs		A8K0P7 J3QKU0 Q96FM1	Q6X784
PDB IDs
Enriched GO Terms of Interacting Partners?
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