IGSF8 and SLIT3

Data Source:
BioGRID (affinity chromatography technology)

		IGSF8	SLIT3
Description		immunoglobulin superfamily member 8	slit guidance ligand 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Space Mitochondrion
	Molecular Function	Protein Binding	Calcium Ion Binding Heparin Binding Roundabout Binding
	Biological Process	Single Fertilization Nervous System Development Skeletal Muscle Tissue Development Cell Motility	Aortic Valve Morphogenesis Atrioventricular Valve Morphogenesis Axon Guidance Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Cell Growth Cellular Response To Hormone Stimulus Roundabout Signaling Pathway Axon Extension Involved In Axon Guidance Negative Chemotaxis Response To Cortisol Ventricular Septum Morphogenesis Apoptotic Process Involved In Luteolysis Negative Regulation Of Chemokine-mediated Signaling Pathway
Pathways			Netrin-1 signaling Signaling by ROBO receptors Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737) Body mass index ( 31217584) Circulating leptin levels in high cardiovascular risk ( 31766143) Circulating leptin levels x sex interaction in high cardiovascular risk ( 31766143) Diastolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009) Gut microbiota (functional units) ( 27694959) Hallux valgus ( 32131869) Height ( 28552196 20881960 25282103 25429064 31562340) Inflammatory skin disease ( 25574825) Menarche (age at onset) ( 25231870) Non-word reading ( 30741946) Treatment resistant depression ( 30468137)
Interacting Genes		16 interacting genes: A2M CD81 CD82 CD9 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-4 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP5-7 TGM1	2 interacting genes: CAPN1 ROBO2
Entrez ID		93185	6586
HPRD ID		09438	04775
Ensembl ID		ENSG00000162729	ENSG00000184347
Uniprot IDs		Q969P0	O75094
PDB IDs
Enriched GO Terms of Interacting Partners?
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