LIN52 and RPS6KL1

Data Source:
BioGRID (biochemical)

		LIN52	RPS6KL1
Description		lin-52 DREAM MuvB core complex component	ribosomal protein S6 kinase like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm DRM Complex	Ribosome
	Molecular Function	Protein Binding	ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Cell Cycle	Protein Phosphorylation
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Chronotype ( 30696823) Macular thickness ( 30535121) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Refractive error ( 32231278) Waist-hip ratio ( 28552196)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) HDL cholesterol levels ( 32203549) Mood instability ( 29187730) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		6 interacting genes: DYRK1A EPM2AIP1 MAGEA6 MYBL2 RBBP4 RBL2
Entrez ID		91750	83694
HPRD ID		18708	18004
Ensembl ID		ENSG00000205659	ENSG00000198208
Uniprot IDs		B3KN83 Q52LA3	B4DSP6 Q9Y6S9
PDB IDs		4YOO 6C48
Enriched GO Terms of Interacting Partners?
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