CD2 and RBM15

Data Source:
BioGRID (biochemical)

		CD2	RBM15
Description		CD2 molecule	RNA binding motif protein 15
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Cell Surface Protein-containing Complex Membrane Raft Anchored Component Of Plasma Membrane	Nucleus Nucleoplasm Nuclear Speck Nuclear Membrane RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding Signaling Receptor Activity Identical Protein Binding Protein Self-association	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Membrane Raft Polarization Apoptotic Process Cell Surface Receptor Signaling Pathway Natural Killer Cell Activation Positive Regulation Of Myeloid Dendritic Cell Activation Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion T Cell Activation Regulation Of T Cell Differentiation Leukocyte Migration Cell-cell Adhesion	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Methylation Branching Involved In Blood Vessel Morphogenesis Positive Regulation Of Transcription Of Notch Receptor Target Dosage Compensation By Inactivation Of X Chromosome Viral Process Thrombopoietin-mediated Signaling Pathway Negative Regulation Of Myeloid Cell Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Transcription, DNA-templated Spleen Development Ventricular Septum Morphogenesis Placenta Blood Vessel Development
Pathways		Cell surface interactions at the vascular wall
Drugs		Alefacept Siplizumab
Diseases
GWAS		Body mass index ( 28552196) Gout (normal type) ( 32238385) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		21 interacting genes: CD247 CD2AP CD2BP2 CD4 CD48 CD5 CD53 CD58 CD59 DNAJC5 FYN LCK LGALS1 LINC00311 LYAR MXD1 PSTPIP1 PTPRC SH3KBP1 SP1 UBC	12 interacting genes: ABI1 CALCOCO2 CEP44 CLK1 CNOT4 DDX17 LZTS2 MAPK8 NAV2 PRMT1 SRPK2 TSPYL2
Entrez ID		914	64783
HPRD ID		01750	05832
Ensembl ID		ENSG00000116824	ENSG00000162775
Uniprot IDs		P06729 Q53F96	Q96T37
PDB IDs		1CDB 1GYA 1HNF 1L2Z 1QA9 2J6O 2J7I
Enriched GO Terms of Interacting Partners?
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