MTMR6 and TRIM38

Data Source:
BioGRID (pull down)

		MTMR6	TRIM38
Description		myotubularin related protein 6	tripartite motif containing 38
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Membrane Ruffle Membrane Perinuclear Region Of Cytoplasm	Cellular_component Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Phosphatidylinositol-3-phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Protein Dephosphorylation Phosphatidylinositol Biosynthetic Process Endocytosis Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway
Pathways		Synthesis of PIPs at the plasma membrane	Interferon gamma signaling
Drugs
Diseases
GWAS		Metabolite levels ( 31628463) Triglyceride levels ( 32203549)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cardiac hypertrophy ( 21348951) Fish- and plant-related diet ( 32066663) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: AATK ALKBH4 AMOTL2 ERBB3 ERBB4 LMTK2 MTMR9 MTNR1B MTUS2 NMI PTK7 RARG ROR2 TRIM27	30 interacting genes: ATXN1 BYSL EIF1B GMCL1 GORASP2 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 MTURN PIAS4 PSMA4 RFC5 RIPK1 RNF4 SDCBP STXBP1 TCEA2 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U ZNF764
Entrez ID		9107	10475
HPRD ID		11946	15555
Ensembl ID		ENSG00000139505	ENSG00000112343
Uniprot IDs		Q9Y217	A0A024QZY4 O00635
PDB IDs		2YF0
Enriched GO Terms of Interacting Partners?
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