TBX19 and GSDME

Data Source:
BioGRID (two hybrid)

		TBX19	GSDME
Description		T-box transcription factor 19	gasdermin E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytosol Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Cardiolipin Binding
	Biological Process	Mesoderm Formation Cell Fate Specification Somitogenesis Heart Morphogenesis Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Pituitary Gland Development Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Sensory Perception Of Sound Cell Death Negative Regulation Of Cell Population Proliferation Positive Regulation Of MAPK Cascade Inner Ear Receptor Cell Differentiation Necrotic Cell Death Pyroptosis Cellular Response To Tumor Necrosis Factor Cellular Response To Virus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases		Adrenocorticotropic hormone deficiency; Isolated ACDH deficiency (IAD)	Deafness, autosomal dominant
GWAS
Interacting Genes		15 interacting genes: GCM2 HGS HOXC8 IRX6 LONRF1 NEDD9 NR5A1 PITX1 POGZ PRR35 RAB2B TBX6 TFG VENTX ZIC1	3 interacting genes: ITGB1BP1 PTN TIFA
Entrez ID		9095	1687
HPRD ID		05214	02996
Ensembl ID		ENSG00000143178	ENSG00000105928
Uniprot IDs		B3KRD9 O60806	A0A024RA58 A4FVA8 O60443
PDB IDs
Enriched GO Terms of Interacting Partners?
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