NAT8 and SSB

Data Source:
BioGRID (affinity chromatography technology)

		NAT8	SSB
Description		N-acetyltransferase 8 (putative)	small RNA binding exonuclease protection factor La
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Chromosome, Telomeric Region Nucleus Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Cysteine-S-conjugate N-acetyltransferase Activity	TRNA Binding RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Sequence-specific MRNA Binding
	Biological Process	Glutathione Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Response To Drug Negative Regulation Of Apoptotic Process Cellular Protein Metabolic Process Amyloid-beta Metabolic Process	TRNA 5'-leader Removal TRNA Modification TRNA Export From Nucleus TRNA Processing Histone MRNA Metabolic Process TRNA 3'-end Processing Nuclear Histone MRNA Catabolic Process IRES-dependent Viral Translational Initiation Protein Localization To Cytoplasmic Stress Granule
Pathways		Amyloid fiber formation	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 29545352) Serum metabolite levels ( 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)	Common carotid intima-media thickness in HIV infection ( 29206233) Fasting glucose change (long-term) ( 31263163) Glomerular filtration rate in diabetes ( 29703844)
Interacting Genes		29 interacting genes: ARL13B ATP6V0E1 BIK CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MFSD14B MTIF3 REEP2 SAR1A SLC10A6 SMAD4 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TSPAN31 YIPF4	11 interacting genes: APP CDC42 CSNK2A1 CSNK2B GZMH HMGA1 IL7R NCL PTEN SPIB SPP1
Entrez ID		9027	6741
HPRD ID		08413	00168
Ensembl ID		ENSG00000144035	ENSG00000138385
Uniprot IDs		Q9UHE5	P05455
PDB IDs			1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
Enriched GO Terms of Interacting Partners?
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