CACNA1I and TST

Data Source:
HPRD (in vitro)

		CACNA1I	TST
Description		calcium voltage-gated channel subunit alpha1 I	thiosulfate sulfurtransferase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Voltage-gated Calcium Channel Complex Neuron Projection	Extracellular Space Mitochondrion Mitochondrial Matrix
	Molecular Function	Voltage-gated Calcium Channel Activity Voltage-gated Sodium Channel Activity Protein Binding Low Voltage-gated Calcium Channel Activity	Thiosulfate Sulfurtransferase Activity 5S RRNA Binding
	Biological Process	Signal Transduction Neuronal Action Potential Flagellated Sperm Motility Sleep Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential	Sulfur Amino Acid Catabolic Process Cyanate Catabolic Process Transsulfuration Epithelial Cell Differentiation RRNA Import Into Mitochondrion RRNA Transport
Pathways		NCAM1 interactions	Sulfide oxidation to sulfate Degradation of cysteine and homocysteine
Drugs		Ergocalciferol Enflurane Amlodipine Spironolactone Cinnarizine Paramethadione Zonisamide Nifedipine Amiodarone Mibefradil Flunarizine Nylidrin Cannabidiol Trimebutine Benidipine Efonidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols	S-Mercaptocysteine
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Household income (MTAG) ( 31844048) IgG glycosylation ( 23382691) Intelligence (MTAG) ( 29326435) Negative urgency ( 30718321) Refractive error ( 32231278) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Schizophrenia ( 28991256 22883433 29483656 30285260)	Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919)
Interacting Genes			2 interacting genes: MT-ND1 PRSS1
Entrez ID		8911	7263
HPRD ID		10500	01583
Ensembl ID		ENSG00000100346	ENSG00000128311
Uniprot IDs		Q9P0X4	A0A384NKQ2 Q16762
PDB IDs
Enriched GO Terms of Interacting Partners?
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